Results 71 to 80 of about 3,167,550 (306)

INVEST in Change: Institutional transformation for sustainable European research cooperation - Final report for INVEST4EXCELLENCE project [PDF]

open access: yes
INVEST4EXCELLENCE (I4E) was a Horizon2020 -funded research and development project which aimed to strengthen the Research, Development and Innovation (RDI) potential of the international European University Alliance INVEST, with Karelia University of ...
Muhonen, Tiina   +2 more
core  

BCT480: Environmental Assessment / Faculty of Applied Sciences [PDF]

open access: yes, 2018
This course is an introduction to environmental control for B. Sc. (Hons.) Bio-Composite Technology in the Faculty of Applied Sciences. The course provides an overview of many topics in environmental science with particular emphasis on current ...
UiTM, Faculty of Applied Sciences
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Ga@MXene-based flexible wearable biosensor for glucose monitoring in sweat

open access: yesiScience
Summary: Most wearable biosensors struggle to balance flexibility and conductivity in their sensing interfaces. In this study, we propose a wearable sensor featuring a highly stretchable, three-dimensional conductive network structure based on liquid ...
Wensi Zhang   +4 more
doaj   +1 more source

FOOD SCIENCE AND APPLIED NUTRITION COLLEGE OF APPLIED SCIENCE

open access: yes, 2020
Honey is a sweet, viscous substance produced by honey bees from the nectar of plants or secretion fromplants or plant-sucking insects. Honeys from different botanical origins may vary in their chemical composition, flavor and color. In this study, Coffea arabica and Vernonia amygdalina honey of Ethiopia investigated.
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Targeting nanoparticles to lung cancer-derived A549 cells based on changes on interstitial stiffness in biomimetic models

open access: yesiScience
Summary: The mechanical properties and forces of the extracellular environment modulate alveolar epithelial cell behavior. To model cancer/fibrosis associated stiffening and dynamic stretch, a biomimetic device was developed that imitates the active ...
Afia Ibnat Kohon   +8 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Drug nanocrystals: Surface engineering and its applications in targeted delivery

open access: yesiScience
Summary: Drug nanocrystals have received significant attention in drug development due to their enhanced dissolution rate and improved water solubility, making them effective in overcoming issues related to drug hydrophobicity, thereby improving drug ...
Phattalapol Lhaglham   +8 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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