Results 101 to 110 of about 16,264,514 (388)

Multicenter study for CH-VAD as a fully magnetically levitated left ventricular assist device

open access: yesiScience
Summary: The CH-VAD is a fully magnetically levitated left ventricular assist device (LVAD) designed for optimized hemocompatibility. This study evaluates the clinical outcomes of 77 patients implanted with the CH-VAD across seven centers in China from ...
Yifan Lu   +12 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Basin dependencies of tropical cyclone genesis environment and possible future changes revealed by machine learning methods

open access: yesiScience
Summary: Tropical cyclone (TC) genesis mechanisms remain debated, complicating predictions of climate change impacts. This study uses principal-component analysis (PCA), confidence ellipses, and correlation circles to analyze TC genesis environments ...
QiFeng Qian   +4 more
doaj   +1 more source

Overeducation among graduates from universities of applied sciences: Determinants and consequences

open access: yes, 2015
This paper investigates the phenomenon of qualification mismatch (overeducation) among graduates from universities of applied sciences. Using data from the Swiss graduate surveys, it analyses the incidence of mismatch, determinants, and the connections ...
Andrea Diem
semanticscholar   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Advances in nanoparticle-based radiotherapy for cancer treatment

open access: yesiScience
Summary: Radiotherapy has long been recognized as an effective conventional approach in both clinical and scientific research, primarily through mechanisms involving DNA destruction or the generation of reactive oxygen species to target tumors.
Meijuan He   +7 more
doaj   +1 more source

Blackboard Use by Faculty Members in the Colleges of Applied Sciences in the Sultanate of Oman

open access: yes, 2015
This research was conducted to investigate the use of Blackboard by faculty members in the Colleges of Applied Sciences in the Sultanate of Oman and the factors affecting their use.
Salim Abdullah AlNaibi   +2 more
semanticscholar   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Fitness or socializing - A multi-dimensional analysis of online fitness communities users

open access: yesiScience
Summary: The digital and social network revolution in the fitness industry will provide consumers with opportunities to achieve their healthy and active lifestyle goals both online and offline.
Lei Wang   +3 more
doaj   +1 more source

Reactor monitoring and safeguards using antineutrino detectors

open access: yes, 2008
Nuclear reactors have served as the antineutrino source for many fundamental physics experiments. The techniques developed by these experiments make it possible to use these very weakly interacting particles for a practical purpose.
Applied Antineutrino Physics   +16 more
core   +1 more source

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