Results 121 to 130 of about 16,264,514 (388)

Dynamics of the oral microbiome during orthodontic treatment and antimicrobial advances for orthodontic appliances

open access: yesiScience
Summary: The oral microbiome plays an important role in human health, and an imbalance of the oral microbiome could lead to oral and systemic diseases. Orthodontic treatment is an effective method to correct malocclusion.
Qin Niu   +6 more
doaj   +1 more source

NanoInfoBio: A case-study in interdisciplinary research

open access: yes, 2011
A significant amount of high-impact contemporary scientific research occurs where biology, computer science, engineering and chemistry converge. Although programmes have been put in place to support such work, the complex dynamics of interdisciplinarity ...
Amos, Martyn, Jacobs, Naomi
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Roles and therapeutic opportunities of ω-3 long-chain polyunsaturated fatty acids in lung cancer

open access: yesiScience
Summary: Over the past decades, researchers have continuously investigated the potential functions of long-chain polyunsaturated fatty acids (LCPUFAs) in cancers, including lung cancer.
Jiang Luo   +13 more
doaj   +1 more source

Advances in Natural and Applied Sciences

open access: yes, 2015
Wind energy based electricity generation is becoming economical with the advancement in power electronic technology and efficient control methods. Wind energy is expected to share around 25% of global electricity generation by the year 2030.
J. Biju, D. Shanthi
semanticscholar   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Cutting-edge microneedle innovations: Transforming the landscape of cardiovascular and metabolic disease management

open access: yesiScience
Summary: Cardiovascular diseases (CVDs) and metabolic disorders (MDs) have surfaced as formidable challenges to global health, significantly imperiling human well-being. Recently, microneedles (MNs) have garnered substantial interest within the realms of
Xiaoning Zhang   +10 more
doaj   +1 more source

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