Results 131 to 140 of about 6,667,255 (317)
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
iScienceSummary: Tropical cyclone (TC) genesis mechanisms remain debated, complicating predictions of climate change impacts. This study uses principal-component analysis (PCA), confidence ellipses, and correlation circles to analyze TC genesis environments ...
QiFeng Qian +4 more
doaj
Applied Mathematics at the Weizmann Institute of Science, Israel [PDF]
, 1965 openalex +1 more source
Molecular Oncology, EarlyView.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
wiley +1 more source
The role of platelet-rich plasma in biomedicine: A comprehensive overview
iScienceSummary: Biomedicine has seen significant advancements in the 21st century, with platelet-rich plasma (PRP) playing a crucial role in clinical practice.
Zhixin Zhang +11 more
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The graduation shift of German universities of applied sciences. [PDF]
PLoS One, 2019 Bornmann L, Wohlrabe K, Gralka S.
europepmc +1 more source
Molecular Oncology, EarlyView.Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric +11 more
wiley +1 more source
Multicenter study for CH-VAD as a fully magnetically levitated left ventricular assist device
iScienceSummary: The CH-VAD is a fully magnetically levitated left ventricular assist device (LVAD) designed for optimized hemocompatibility. This study evaluates the clinical outcomes of 77 patients implanted with the CH-VAD across seven centers in China from ...
Yifan Lu +12 more
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