Results 171 to 180 of about 18,900,974 (296)

Physiology and applied sciences in Nepal: 1st annual conference. [PDF]

Extrem Physiol Med, 2014
Thapa GB, Mahotra NB, Pun M.
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Radiation-resistant bacteria in desiccated soil and their potentiality in applied sciences. [PDF]

Front Microbiol
Khan A, Liu G, Zhang G, Li X.
europepmc   +1 more source

Self-report measures of executive functioning are a determinant of academic performance in first-year students at a university of applied sciences. [PDF]

Front Psychol, 2015
Baars MA, Nije Bijvank M, Tonnaer GH, Jolles J.   +3 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Coordinating Qualitative Predictor Variables in an Applied Linear Model: Analysis and Application for Applied Sciences. [PDF]

Cureus
Ahmad WMAW, Ahmed F, Adnan MN.
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Power to the People: Measuring Social Media and Mass Media Impact for Promotion and Tenure in Social and Applied Sciences. [PDF]

High Educ Policy
Metzger IW, Jernigan-Noesi M, Jones SCT, Turner EA, Saleem F, Jackson J, Anderson RE, Bartolomeo LA, Tineo P, Opara I.   +9 more
europepmc   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source