Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Correction: Voučko et al. Gluten-Free Flatbread with Carob Flour and Sourdough: Nutritional Composition, Technological Properties and Storage Stability. <i>Foods</i> 2026, <i>15</i>, 1504. [PDF]
Voučko B +6 more
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Vision-based tactile sensing enhanced by microstructures and lightweight convolutional neural network. [PDF]
Shi M, Zhang Y, Guo X, Yeatman EM.
europepmc +1 more source
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Effects of tibialis anterior contraction on the medial longitudinal arch and hallux valgus angle: A functional anatomical perspective. [PDF]
Aizu N, Kito T, Nishii K, Yamada K.
europepmc +1 more source
Assessment of Anticancer Effect of Rhodium Nanoparticle-based Photodynamic Therapy via Protein-Protein Interaction Network Analysis. [PDF]
Hossein-Khannazer N +5 more
europepmc +1 more source
Automatic early detection of pathological signs following primary total hip arthroplasty using radiographs, clinical scores, and comorbidities. [PDF]
Galante S +5 more
europepmc +1 more source
Correction: Ectomycorrhizal fungal community varies across broadleaf species and developmental stages. [PDF]
Zhao DX +5 more
europepmc +1 more source

