Results 221 to 230 of about 11,399,306 (340)

Attributing climate-change-related disaster displacement responsibilities along global production chains

open access: yesiScience
Summary: Climate change creates hostile living conditions in various regions, provoking climate-driven migration. The literature points to a polarization between the countries responsible for climate change and the regions suffering its consequences ...
Guadalupe Arce   +3 more
doaj  

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

A semi-supervised method using cycle consistency and multi-perspective dilated for SAR-to-optical translation

open access: yesiScience
Summary: Synthetic aperture radar (SAR) is a powerful imaging sensor capable of operating in any weather and at any time, despite its image interpretation poses challenges.
Jinyu Wang   +3 more
doaj  

Higher education teachers’ descriptions of their own learning: a large-scale study of Finnish Universities of Applied Sciences

open access: yes, 2016
Aija Töytäri   +5 more
semanticscholar   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

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