Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
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Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
Science of Semiology: Apply to an Event
Communication materials have initial role in mass communication. Semiology is part of communication and also effective in marketing for traditional worth, it is like compass which give a direction to society in the world. The importance of semiotics and to analyze Eurovision Song Contest, one of the most important musical event of present societies ...
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Optical multilayer thin film structure inverse design: From optimization to deep learning
Summary: Optical multilayer thin film structures have been widely used in numerous photonic domains and applications. The key component to enable these applications is the inverse design.
Taigao Ma, Mingqian Ma, L. Jay Guo
doaj
David C. Lundgren and David J. Knight. Sequential Stages of Development in Sensitivity Training Groups. Journal of Applied Behavioral Science, 1978, 14(2), 204-222 [PDF]
Anthony G. Banet
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The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh+6 more
wiley +1 more source
Book reviewsConcrete structures: repair, waterproofing and protection PerkinsPhilip H. Published by Applied Science Publishers Ltd, London, 1976. Type-set, illustrated, hard-back. 238 × 148 mm. pp. x, 302. ISBN 0 85334 697 6. Price: £16.00. [PDF]
Roy Galbraith
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Chemistry for the Applied Sciences
Katherine Blood Hoffman, Alton C. Kurtz
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