Results 261 to 270 of about 6,938,619 (347)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Correction of the curve of spee using clear aligner therapy: A finite element analysis of three lower anterior intrusion protocols. [PDF]

PLoS One
Guerrero-Vargas JA, Montalvany-Antonucci CC, Velez-Muriel SM, Couto Figueiredo N, Macari S.   +4 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Reply to Song et al.: Acidity-sensitive chemistry promotes sulfate formation in East Asia. [PDF]

Proc Natl Acad Sci U S A
Lin YC, Hattori S, Itahashi S, Zhang YL.
europepmc   +1 more source

Fundamental and Applied Science in the Contemporary Knowledge Society [In Bulgarian]

, 2014
L. Ivancheva
openalex   +1 more source

Systematic Assessment of the Prerequisites for Institutional RDM Services at a German University of Applied Sciences

Dąbrowska, Paulina Anna, Schneidenbach, Esther, Heister, Eske, Simon, Lena, Dabrowski, Wojtek   +4 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Corrigendum to 'Emerging cell-based and cell-free therapeutic strategies for vitiligo' [J. Transl. Autoimmun., 11 (2025), 100331]. [PDF]

J Transl Autoimmun
Gholijani N, Noori E, Zarei-Behjani Z, Rezaee D, Khodaei M, Darya G, Mehdinejadiani K, Dehghan Z.   +7 more
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Correction: I speak Tele outlines the design of a digitized dysarthria assessment. [PDF]

Sci Rep
Selvanayakam S, Giovanoli S, Slot A, Du E, Menard T, Bendel O, Easthope Awai C, Bauer CM.   +7 more
europepmc   +1 more source