Results 61 to 70 of about 4,649,929 (326)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Mathematical Modeling and Stability Analysis of Systemic Risk in the Banking Ecosystem

Journal of Applied Mathematics, 2023
This paper investigates the dynamics of systemic risk in banking networks by analyzing equilibrium points and stability conditions. The focus is on a model that incorporates interactions among distressed and undistressed banks. The equilibrium points are
Irène Irakoze, Fulgence Nahayo, Dennis Ikpe, Samuel Asante Gyamerah, Frederi Viens   +4 more
doaj   +1 more source

The duality diagram in data analysis: Examples of modern applications

, 2012
Today's data-heavy research environment requires the integration of different sources of information into structured data sets that can not be analyzed as simple matrices.
De la Cruz, Omar, Holmes, Susan
core   +1 more source

ON THE PERFORMANCE OF NONPARAMETRIC SPECIFICATION TESTS IN REGRESSION MODELS [PDF]

, 2013
Some recently developed nonparametric specification tests for regression models are described in a unified way. The common characteristic of these tests is that they are consistent against any alternative hypothesis.
Chesborough HW, Chesbrough H, Chesbrough HW, Chesbrough HW, Department for Business, Enterprise and Regulatory Reform, Department of Enterprise, Trade and Investment, Department of Enterprise, Trade and Investment, Dunning JH, European Commission, Hewitt-Dundas N, Iansiti M, Jarzabkowski P, Monteny F   +12 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Introductory Applied Statistics [PDF]

, 2023
Bruce Blaine
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Applied Statistics [PDF]

Journal of the Royal Statistical Society Series C: Applied Statistics, 2022
  +4 more sources

Response Analysis of Projectile System Under Gaussian Noise Excitation Using Path Integral Method

International Journal of Aerospace Engineering
During flight, projectiles are subject to uncertainties such as aerodynamic forces, wind gusts, and measurement errors; all of which significantly affect their stability and accuracy.
Liang Wang, Xinyi Li, Jiahui Peng, Zhonghua Zhang, Shuangqi Dong   +4 more
doaj   +2 more sources

Discussion of: Treelets--An adaptive multi-scale basis for sparse unordered data

, 2008
Discussion of "Treelets--An adaptive multi-scale basis for sparse unordered data" [arXiv:0707.0481]Comment: Published in at http://dx.doi.org/10.1214/08-AOAS137B the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of ...
Bickel, Peter J., Ritov, Ya'acov
core   +1 more source