Results 121 to 130 of about 142,782 (274)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Investigating Disparities in Physical Therapy Utilization: An Intersectionality Perspective

Archives of Rehabilitation Research and Clinical Translation
Objective: To investigate the role of race, ethnicity, language, insurance payor, and socioeconomic status, both individually and through an intersectional framework, on outpatient physical therapy (PT) utilization.
Lauren Rimmel, PT, DPT, Kathleen Taglieri-Noble, PT, DPT, Rebecca Pham, PT, DPT, Joseph Tolland, PT, DPT, Saloni Doshi, PT, DPT, Nicholas Capobianco, PT, DPT, Anshul Kumar, PhD   +6 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

An Electronic Health Record–Based Automated Self-Rescheduling Tool to Improve Patient Access: Retrospective Cohort Study

Journal of Medical Internet Research
BackgroundIn many large health centers, patients face long appointment wait times and difficulties accessing care. Last-minute cancellations and patient no-shows leave unfilled slots in a clinician’s schedule, exacerbating delays ...
Smitha Ganeshan, Andrew W Liu, Anne Kroeger, Prerna Anand, Richard Seefeldt, Alexis Regner, Diana Vaughn, Anobel Y Odisho, Michelle Mourad   +8 more
doaj   +1 more source

Indicators for dental appointment scheduling in primary health care: a national cross-sectional study. [PDF]

BMC Public Health, 2021
Melo EA, Probst LF, Guerra LM, Tagliaferro EPDS, De-Carli AD, Pereira AC.   +5 more
europepmc   +1 more source

Appointment Scheduling with Delay Tolerance Heterogeneity

INFORMS Journal on Computing
In this study, we investigate an appointment sequencing and scheduling problem with heterogeneous user delay tolerances under service time uncertainty. We aim to capture the delay tolerance effect with heterogeneity, in an operationally effective and computationally tractable fashion, for the appointment scheduling problem.
Shuming Wang, Jun Li, Marcus Ang, Tsan Sheng Ng   +3 more
openaire   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Developing a Model for Dynamic Schedule of Heart Surgery based on Patient\'s Maximum Delay

بیمارستان, 2019
Background: The operating rooms in each health center are one of the most sensitive units in the center, whereas scheduling and scheduling operations are in particular importance and their optimization has a significant effect on the optimization of the ...
Iman Dehghan, Bakhtiar Ostadi, Saeid Hosseini   +2 more
doaj  

The Effect of Three Key Administrative Errors on Patient Trust in Physicians: Prescription Errors, Confidentiality Breaches, and Appointment Scheduling Omissions

Journal of General and Family Medicine
Background Understanding how administrative errors, such as prescription and appointment scheduling omissions, and patient confidentiality breaches impact trust in physicians is crucial for improving patient‐physician relationships and healthcare ...
Tetsuro Aita, Yoshia Miyawaki, Yu Katayama, Kosuke Sakurai, Nao Oguro, Takafumi Wakita, Nobuyuki Yajima, Ashwin B. Gupta, Noriaki Kurita   +8 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source