Results 201 to 210 of about 19,821 (264)

Exploring the Association Between Adverse Childhood Experiences and Missed Primary Care Appointments in Adult Patients. [PDF]

Perm J
Anjum P, Evenhuis BS, Zhang R, Britton C, Fleurant M.   +4 more
europepmc   +1 more source

Rewiring Pyroptosis to Potentiate Cancer Immunotherapy via a Gasdermin D Agonist Bypassing Caspase‐3

Advanced Science, EarlyView.
This work introduces a small‐molecule agonist, DIBDO, that bypasses Casp‐3 to directly trigger GSDMD‐mediated pyroptosis in tumors. Activated by glutathione, DIBDO generates singlet oxygen and molecular iodine, blocking Casp‐3 pathways and inducing immunogenic cell death.
Dan Zhao, Lingling Zhang, Yue Wen, Lianghui Cheng, Sidan Tian, Fanling Meng, Liang Luo   +6 more
wiley   +1 more source

Is 10 minutes sufficient? Follow-up consultation in Ecuadorian Social Security health systems. [PDF]

Front Public Health
Quiroz-Cárdenas D, Quiroz-Cárdenas F, López-Gil JF.   +2 more
europepmc   +1 more source

SOX5 Orchestrates Malignant Evolution via Promoter‐Centric Chromatin Remodeling in MYC‐Driven B‐Cell Lymphoma

Advanced Science, EarlyView.
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao, Zhenyuan Jia, Xiao‐Qin Mu, Ruilin Wang, Jianli Ma, Qingyuan Zhang, Yuwei Deng   +6 more
wiley   +1 more source

Parents' precarious work schedules and children's asthma management. [PDF]

BMC Public Health
Quinn K, Perez K, Schneider D.
europepmc   +1 more source

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source

Organizing everyday management in older adults with multimorbidity: a qualitative study from a time-geography perspective. [PDF]

Front Med (Lausanne)
Lin H, Lin H, Miao Z, Chen Y, Wang Z, Wang X.   +5 more
europepmc   +1 more source

Access to Technology-Mediated Community Mental Health Care Among Low-Socioeconomic Status Consumers With Serious Mental Illness: Qualitative Study. [PDF]

JMIR Form Res
Stone AK, Veinot TC.
europepmc   +1 more source

A Survey of Current Audiology Practice in Adult Cochlear Implant Programs and Its Impact on Access to Care. [PDF]

Ear Hear
Zwolan TA, Holcomb M, Buck B, Adkins W, Snapp H, Prentiss S.   +5 more
europepmc   +1 more source