Results 111 to 120 of about 462,438 (309)
Investigation the Strategic Importance of Delegation of Authority for Governmental Organizations Effectiveness (Case Study: Municipality of Mashhad) [PDF]
بهبود مدیریت, 2015 Today, large modern organizations are facing with a variety of practices and issues and different problems, so it is necessary to culture making in field of delegation of authority from senior managers to managers at lower levels and to decentralizing in
Mohammad Lagzian, Seyed Reza Nouri
doaj
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Youth Appreciation of The Existence of Historical Buildings (Vredeburg Fort)
Dimensi: Journal of Architecture and Built EnvironmentYogyakarta is a city that has a diverse history and cultural heritage both physically and non-physically. Physically in the form of buildings - historical heritage buildings such as the Vredeburg Fort building which is one of the relics of VOC ...
Muhammad Hasan Al Bashri +1 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
MODERN CHALLENGES TO THE MANAGEMENT OF PUBLIC INSTITUTIONS. THE INFLUENCE OF APPRECIATION ON INSTITUTIONAL DYNAMICS, WITH A FOCUS ON MILITARY ORGANIZATIONS [PDF]
Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria EconomieThe modernization of the management of public institutions faces difficulties on different leves, first one being that most of the strategic management studies are done on private firms. The private and public sector differ vastly.
MARIUS-EMANUEL CARAGEA
doaj
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
BeveragesThe popular appreciation of dry white wines is most frequently directed to young wines. However, present consumption trends comprise the valorisation of aged dry white wines. Therefore, the present work was aimed at the sensory analysis of aged dry white
Marta Esteves +2 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source