Results 41 to 50 of about 478,912 (244)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Virtual art exhibitions during quarantine and their impact on aesthetic appreciation movement
Journal of Architecture, Art & Humanistic ScienceWith the spread of covid-19 all over the world in 2020, which also crept into Egypt, most countries had been prompted to have a considerable period of compulsory quarantine that affected different aspects of human activities.
Dr. Basma Mounir Mohamed Samir ghazy
doaj +1 more source
Jurnal Pendidikan dan Kebudayaan, 2015 This article aims to examine the material of literary works used in Indonesian teaching materials in senior secondary schools. This study focuses on the analysis themes of literary works. Therefore, this research employs structural theory approach. In
Lustantini Septiningsih
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Journal of Architecture, Art & Humanistic ScienceThe rigidity of the classical criticism model followed in reading the works of Neoclassicism has caused the transformation of the works of classical criticism into a set of readings with fixed judgments, even with the difference in the work and artist ...
Assisst.Prof. Hala Ahmed Abd Elsamea Emara
doaj +1 more source
Optimization of Humanistic Education in the Integrated Islamic Primary School
Al Ibtida: Jurnal Pendidikan Guru MI, 2019 Only a few primary schools apply humanistic education. This could be viewed from the students’ moral decadence and the process of dehumanizing education.
Asep Kurniawan
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source