Results 151 to 160 of about 165,775 (267)

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Mental Health Nurses' Perceived Appropriateness of Coercive Measures and Security Technologies in Psychiatric Settings: A National Cross-Sectional Study. [PDF]

J Nurs Scholarsh
Anastasi G, Latina R, Longobucco Y, Stievano A, Bambi S.   +4 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Corrigendum: Choosing wisely in pediatric healthcare: a narrative review

Frontiers in Pediatrics
Sandra Trapani, Sandra Trapani, Alessandra Montemaggi, Giuseppe Indolfi, Giuseppe Indolfi   +4 more
doaj   +1 more source

Modulate Obesity and relateD metabolic complIcations For Yielding improvements in IBD outcomes (MODIFY-IBD): consensus on obesity and cardiometabolic comorbidities in inflammatory bowel disease using systematic reviews and the RAND/UCLA appropriateness method. [PDF]

BMJ Open
Devi J, Samaan S, Sehgal P, Mohamed M, Vincent M, Coombs S, Doering M, Barnes EL, Johnson AM, Yarur AJ, Deepak P.   +10 more
europepmc   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Implementation tendencies and expert perspectives on physician-performed prehospital endotracheal intubation in Japan: Findings from the first round of a Delphi survey. [PDF]

PLoS One
Taniguchi H, Omori K, Nagasawa H, Ohsaka H, Yanagawa Y.   +4 more
europepmc   +1 more source

Between appropriation and appropriateness

, 2019
openaire   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

How can a remotely delivered, personalised physical activity intervention for people with high risk of breast, lung and bowel cancer recurrence be implemented in England? Protocol for a mixed-methods process evaluation embedded in a feasibility basket trial. [PDF]

BMJ Open
Jackson G, Pearson M, Bullock AF, Cohen J, Huang C, Lind M, Saxton J, Wilson C, Twiddy M, Forbes CC.   +9 more
europepmc   +1 more source