Results 181 to 190 of about 149,758 (276)

Stable and Reliable Approximate Bayesian Inference

Stable and Reliable Approximate Bayesian Inference
学位の種別: 課程博士|審査委員会委員 : （主査）東京大学准教授 佐藤 一誠, 東京大学教授 岡田 真人, 東京大学准教授 小林 亮太, 東京大学講師 石田 隆, 大阪大学講師 二見 ...
openaire  

Addressing Small Data Challenges in Biopharmaceutical Development and Manufacturing: A Mini Review of Multi‐Fidelity Techniques

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The growing demand for biopharmaceutical products reflects their effectiveness in medical treatments. However, developing new biopharmaceuticals remains a major bottleneck, often taking up to a decade before market approval. Machine learning (ML) models have the potential to accelerate this process, but their success depends on access to large
Mohammad Golzarijalal, Uwe Aickelin, Ellen Otte   +2 more
wiley   +1 more source

Decision, Inference, and Information: Formal Equivalences Under Active Inference. [PDF]

Entropy (Basel)
Sweeney P, Ruiz-Serra J, Harré MS.
europepmc   +1 more source

A Modular Mechanistic In Silico Model for In Vitro Transcription Process Yield and Product Quality Prediction

Biotechnology and Bioengineering, EarlyView.
ABSTRACT In vitro transcription (IVT) plays a critical role in the manufacture of mRNA vaccines and therapeutics. Optimizing mRNA yield and ensuring product quality, such as capping efficiency and integrity, are essential but mechanistically complex. This study presents a modular mechanistic model of the IVT process to advance scientific understanding ...
Keqi Wang, Keilung Choy, Eli Reiser, Jinxiang Pei, Hua Zheng, Aparajita Dasgupta, Fuqiang Cheng, Guogang Dong, Bhanu Chandra Mulukutla, Joshua Mannheimer, Carolyn Huang, Hooman Farsani, Wei Xie   +12 more
wiley   +1 more source

Bayesian teaching enables probabilistic reasoning in large language models. [PDF]

Nat Commun
Qiu L, Sha F, Allen K, Kim Y, Linzen T, van Steenkiste S.   +5 more
europepmc   +1 more source

Adaptive Genomic Divergence Across Altitudes in Capsella bursa‐pastoris

Biological Diversity, EarlyView.
Genomic divergence was observed between high‐altitude and low‐altitude populations of Capsella bursa‐pastoris in China, consistent with an important role of ecological factors. Candidate adaptive loci associated with enhanced energy metabolism, photoprotection, and growth plasticity under altitudinal stress were identified.
Lu Liu, Jia Li, Xin Liu, Xue‐Jun Ge, Hui‐Run Huang   +4 more
wiley   +1 more source

Age-dependent Phylodynamics with Application to Single-cell Lineage Trees. [PDF]

Mol Biol Evol
Mulberry N, Pilarski J, Dinger J, Stadler T.   +3 more
europepmc   +1 more source

Back to Nature or Technology to the Rescue? Climate Managers' Preferences for Investment in Carbon Dioxide Removal

Business Strategy and the Environment, EarlyView.
ABSTRACT Firms are increasingly looking into carbon dioxide removal (CDR), a set of options to take past emissions of greenhouse gases out of the atmosphere. Often two basic categories of CDR are distinguished: nature‐based solutions, such as planting trees or restoring wetlands, and technology‐based solutions, such as various forms of carbon capture ...
Sabrina Mili, Robert Mai, Rolf Wüstenhagen, Moritz Loock   +3 more
wiley   +1 more source

Coupling Causal Inference and Cross-Modal Recalibration: A Unified Framework for Adaptive Multisensory Perception. [PDF]

Biology (Basel)
Liu J, Huang CC, Zeng F.
europepmc   +1 more source

Innovation Pathways to Carbon Efficiency: Disentangling the Effects of AI, R&D, and Clean Energy Blessings on U.S. Environmental Sustainability

Business Strategy and the Environment, EarlyView.
ABSTRACT The United States (U.S.) faces challenges in achieving its ambitious net‐zero carbon emissions target by 2050, with current emissions having fallen by less than 1% in 2024. Despite an investment of $500 billion in low‐carbon resources while holding the second‐largest green technology patent portfolio globally, it is further imperative to ...
Md Zubair Ahmad, Jewel Rana, Mohammad Fakhrul Islam, Md Nazmul Islam Jihad, Md. Rashed, Md. Kamal Uddin   +5 more
wiley   +1 more source