Results 221 to 230 of about 808,804 (331)

A versatile coherent Ising computing platform. [PDF]

Light Sci Appl
Wei H, Ai C, Guo P, Jia B, Yuan L, Song H, Chen S, Cao C, Wu J, Ju C, Ma Y, Fan J, Hu M, Wang C, Wen K.   +14 more
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Achieving high precision in analog in-memory computing systems. [PDF]

Npj Unconv Comput
Mannocci P, Larelli G, Bonomi M, Ielmini D.   +3 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Resource Allocation and Trajectory Planning in Integrated Sensing and Communication Enabled UAV-Assisted Vehicular Network. [PDF]

Sensors (Basel)
Song M, Zhang W, Bai J.
europepmc   +1 more source

Architecture-Aware Approximate Computing [PDF]

, 2019
Mustafa Karaköy, Orhan Kislal, Xulong Tang, Mahmut Kandemir, Meenakshi Arunachalam   +4 more
openalex   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Harnessing Approximate Computing for Machine Learning

Salar Shakibhamedan, Amin Aminifar, Luke Vassallo, Nima TaheriNejad   +3 more
openalex   +1 more source

Chebyshev Approximated Variational Coupled Cluster for Quantum Computing [PDF]

Luca Erhart, Yuichiro Yoshida, Viktor Khinevich, Wataru Mizukami   +3 more
openalex   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source