Results 111 to 120 of about 501,542 (292)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Processi di controllo con parametri distribuiti in insiemi non limitati. Controllabilità con luogo iniziale variabile

open access: yesLe Matematiche, 2005
We study the controllability with variable initial locus of some distributed parameter linear control system.In this setting, we study the controllability of such system from a given initial state, to be attained on the variable initial locus, to an ...
Giuseppe Pulvirenti   +2 more
doaj  

Approximate Controllability Of Semilinear Systems Using Integral Contractors

open access: yes, 1995
In this article, a non-autonomous (time-varying) semilinear system is considered and its approximate controllability is investigated. The notion of 'bounded integral contractor', introduced by Altman, has been exploited to obtain sufficient conditions ...
George, Raju K
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

On controllability of linear stochastic systems

open access: yes, 2000
We discuss several concepts of controllability for partially observable stochastic systems: complete controllability, approximate controllability, controllability and S-controllability, and show that complete and approximate controllability notions are ...
Denker, A, Mahmudov, NI
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Approximate controllability of impulsive semilinear evolution equations in Hilbert spaces

open access: yes
Several dynamical systems in fields such as engineering, chemistry, biology, and physics show impulsive behaviour by reason of unexpected changes at specific times. These behaviours are described by differential systems under impulse effects. The current
Asadzade, Javad A., Mahmudov, Nazim I.
core   +2 more sources

Approximate Controllability of Fractional Evolution System on Non-Dense Domain [PDF]

open access: yes
This article explores the existence and approximate controllability of integral solutions for Hilfer fractional evolution equations in a non-dense domain.
Kumar, Umesh   +3 more
core   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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