Results 61 to 70 of about 32,211 (287)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Approximate controllability of fractional nonlocal evolution equations with multiple delays

Advances in Difference Equations, 2017
This paper deals with the existence and approximate controllability for a class of fractional nonlocal control systems governed by abstract fractional evolution equations with multiple delays.
He Yang, Elyasa Ibrahim
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Results on partial approximate controllability of fractional control systems in Hilbert spaces with conformable derivatives

AIP Advances
This paper investigates partial approximate controllability of fractional linear and semi-linear control systems involving the conformable derivative.
Maher Jneid
doaj   +1 more source

Approximate controllability of a second-order neutral stochastic differential equation with state dependent delay

Nonlinear Analysis, 2016
In this paper, the existence and uniqueness of mild solution is initially obtained by use of measure of noncompactness and simple growth conditions. Then the conditions for approximate controllability are investigated for the distributed second-order ...
Sanjukta Das, Dwijendra N. Pandey, Nagarajan Sukavanam   +2 more
doaj   +1 more source

Approximate controllability of Atangana-Baleanu fractional neutral delay integrodifferential stochastic systems with nonlocal conditions☆

Ain Shams Engineering Journal, 2023
The study of approximate controllability results ensures the essential conditions required for a solution. Keeping the importance of the study, we initiate the existence and approximate controllability an Atangana-Baleanu-Caputo (ABC)-fractional order ...
Yong-Ki Ma, C. Dineshkumar, V. Vijayakumar, R. Udhayakumar, Anurag Shukla, Kottakkaran Sooppy Nisar   +5 more
doaj   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior, Edmara Bazoni Soares Maia, Soad Fuentes‐Alabí, Courtney E. Sullivan, Monnie Abraham, Mauricio Maza, Liliana Vásquez Ponce, Regina Aparecida Garcia Lima   +7 more
wiley   +1 more source

A note on existence and approximate controllability outcomes of Atangana–Baleanu neutral fractional stochastic hemivariational inequality

Results in Physics, 2022
This article is primarily targeting the approximate controllability results of Atangana–Baleanu neutral fractional stochastic hemivariational inequality.
C. Dineshkumar, R. Udhayakumar, V. Vijayakumar, Kottakkaran Sooppy Nisar, Anurag Shukla, Abdel-Haleem Abdel-Aty, Mona Mahmoud, Emad E. Mahmoud   +7 more
doaj   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source