Results 101 to 110 of about 742,791 (250)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Comparison of Eeg Approximate Entropy and Complexity Measures of Depth of Anaesthesia during Inhalational General Anaesthesia

open access: yes, 2012
Approximate entropy (ApEn) and Lempel-Ziv complexity (LZC), which are nonlinear quantification methods of the regularity of electroencephalogram (EEG) signals, have recently been proposed as measures of the depth of anaesthesia.
FAN, SHOU-ZEN;YEH, JIA-RONG;CHEN, BO-CUN;SHIEH, JIANN-SHING   +1 more
core  

Investigating the synchronization of hippocampal neural network in response to acute nicotine exposure

open access: yesJournal of NeuroEngineering and Rehabilitation, 2010
Previous studies suggested that γ oscillations in the brain are associated with higher order cognitive function including selective visual attention, motor task planning, sensory perception, working memory and dreaming REM sleep.
Akay Metin, Akay Yasemin M, Akkurt David
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Driving Fatigue Classification Based on Fusion Entropy Analysis Combining EOG and EEG

open access: yesIEEE Access, 2019
The rising number of traffic accidents has become a major issue in our daily life, which has attracted the concern of society and governments. To deal with this issue, in our previous study, we have designed a real-time driving fatigue detection system ...
Hongtao Wang   +5 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Improved method for detecting weak abrupt information based on permutation entropy

open access: yesAdvances in Mechanical Engineering, 2017
As a dynamic detecting method for abrupt information, permutation entropy could effectively reflect the subtle change in time series data, which is also simple and can be computed conveniently.
Yongjun Shen, Junfeng Wang, Shaopu Yang
doaj   +1 more source

Home - About - Disclaimer - Privacy