Results 41 to 50 of about 6,197 (262)

A Low Power Radix-4 Booth Multiplier With Pre-Encoded Mechanism

IEEE Access, 2020
The radix-4 Booth algorithm is widely used to improve the performance of multiplier because it can reduce the number of partial products by half. However, numerous additional encoders and decoders would cause the power consumption of the Booth multiplier
Yen-Jen Chang, Yu-Cheng Cheng, Shao-Chi Liao, Chun-Huo Hsiao   +3 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Comparison of Lagrange multipliers for telegraph equations

Ain Shams Engineering Journal, 2018
In this paper, we likewise calculate exact langrage multiplier and it progressively connects to the definite results of telegraph equations. This study witnesses the advantages of Exact Lagrange multipliers and their coupling with Variational Iteration ...
Muhammad Hamid, Muhammad Usman, Tamour Zubair, Syed Tauseef Mohyud-Din   +3 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Design of Power Efficient Approximate Multiplier Using Enhanced Adder Compressors

Electrica
This study shows a new design for an approximation unsigned multiplier that keeps good computational accuracy while cutting down on size and power use significantly.
Dande Parameswara Upendranath, V Krishnanaik   +1 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

FPGA-Based Approximate Multiplier for FP8

2025 IEEE 33rd Annual International Symposium on Field-Programmable Custom Computing Machines (FCCM)
The 8-bit floating-point (FP8) data format has been increasingly adopted in neural network (NN) computations due to its superior dynamic range compared to traditional INT8. However, FP8-based multiplication, a core operation in NNs, still incurs significant power consumption.
Ruiqi Chen 0001, Yangxintong Lyu, Han Bao, Jiayu Liu, Yanxiang Zhu, Shidi Tang, Ming Ling, Bruno da Silva 0001   +7 more
openaire   +2 more sources

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source