Results 41 to 50 of about 7,113 (299)
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
FPGA-Based Multi-Level Approximate Multipliers for High-Performance Error-Resilient Applications
IEEE Access, 2020 This paper presents approximate multipliers which are efficiently deployed on Field Programmable Gate Arrays (FPGAs) by using newly proposed approximate logic compressors at different levels of accuracy.
Nguyen Van Toan, Jeong-Gun Lee
doaj +1 more source
Error Analysis of Approximate Array Multipliers
CoRR, 2019 Approximate computing is a nascent energy-efficient computing paradigm suitable for error-tolerant applications. However, the value of approximation error depends on the applied inputs where individual output error may reach intolerable level while the average output error is acceptable.
Mahmoud Masadeh +2 more
openaire +2 more sources
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Surveys in Mathematics and its Applications, 2018 Let A be a Banach algebra, X be a Banach left A-module and n ≥ 2 be an integer. A bounded linear operator T: A → X is called an n-Jordan multiplier if for each a ∈ A, T(an)=a· T(an-1).
Mohammad Fozouni
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
A Low Power Radix-4 Booth Multiplier With Pre-Encoded Mechanism
IEEE Access, 2020 The radix-4 Booth algorithm is widely used to improve the performance of multiplier because it can reduce the number of partial products by half. However, numerous additional encoders and decoders would cause the power consumption of the Booth multiplier
Yen-Jen Chang +3 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Government spending shocks and the multiplier: New evidence from the U.S. based on natural disasters [PDF]
, 2012 The literature on estimating macroeconomic effects of fiscal policy requires suitable instruments to identify exogenous and unanticipated spending shocks. So far, the instrument of choice has been military build-ups.
Ghosh, Sugata +5 more
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