Results 121 to 130 of about 38,188 (290)

Differentially private approximate pattern matching [PDF]

Differential privacy is the de facto privacy standard in data analysis and widely researched in various application areas. On the other hand, analyzing sequences, or strings, is essential to many modern data analysis tasks, and those data often include ...
Steiner, Teresa Anna
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Approximate parameterized matching

, 2004
Two equal length strings s and s ′ , over alphabets Σs and Σs ′, parameterize match if there exists a bijection π: Σs → Σs ′, such that π(s) = s ′ , where π(s) is the renaming of each character of s via π.
Carmit Hazay, Dina Sokol, Moshe Lewenstein   +2 more
core   +1 more source

Optimization of connection patterns between mobile phones and base stations using quantum annealing

Scientific Reports
In current mobile networks, optimizing which base station a mobile phone in a particular area connects to is crucial for ensuring good communication quality for each mobile phone but presents a challenging combinatorial optimization problem.
Taisei Takabayashi, Shoichi Sudo, Toshihiro Aoki, Shun Seo, Masayuki Ohzeki   +4 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Fast and Practical Approximate String Matching

, 1992
We present new algorithms for approximate string matching based in simple, but efficient, ideas. First, we present an algorithm for string matching with mismatches based in arithmetical operations that runs in linear worst case time for most practical ...
Ricardo A. Baeza-yates, Chris H. Perleberg   +1 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

The sketching complexity of pattern matching

, 2004
. We address the problems of pattern matching and approximate pattern matching in the sketching model. We show that it is impossible to compress the text into a small sketch and use only the sketch to decide whether a given pattern occurs in the text. We
Robert Krauthgamer, Ravi Kumar, Ziv Bar-yossef, T. S. Jayram   +3 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Approximate Fingerprinting to Accelerate Pattern Matching ABSTRACT

, 2008
Pattern matching and analysis over network data streams is increasingly becoming an essential primitive of network monitoring systems. It is a fundamental part of most intrusion detection systems, worm detecting algorithms and many other anomaly ...
Gianluca Iannaccone, Lukas Kencl
core