Results 161 to 170 of about 38,188 (290)

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Approximate regional sequence matching for genomic databases

, 2012
Recent advances in computational biology have raised sequence matching requirements that result in new types of sequence database problems. In this work, we introduce an important class of such problems, the Approximate Regional Sequence Matching (ARSM ...
Theodore Dalamagas (6637886), Dimitris Sacharidis (19993185), Thanasis Vergoulis (6637874), Timoleon Sellis (19981002)   +3 more
core  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

A Logical Characterization for Approximate Matching of Pattern Graphs with Regular Expressions

A graph simulation and its variants are widely used in graph pattern matching. Among them, there have been related works involving the addition of regular expressions to graph patterns, which can discover more meaningful data and solve problems in ...
Jin Wang, Xuelei Chen, Xinyu Cui, Yu Zhang, Xinfei Liao, Zuoli Zhang   +5 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Sassy: fuzzy searching DNA sequences using SIMD. [PDF]

Bioinformatics
Beeloo R, Groot Koerkamp R.
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Approximate String Matching with Gaps

, 2002
In this paper we consider several new versions of approximate string matching with gaps. The main characteristic of these new versions is the existence of gaps in the matching of a given pattern in a text.
Tsakalidis, A., Tsichlas, K., Maxime Crochemore, Crochemore, M, Iliopoulos, Costas S., Tsichlas, K, Christos Makris, Makris, C, Rytter, W, Crochemore, Maxime, Iliopoulos, C, Athanasios Tsakalidis, Tsakalidis, A, Wojciech Rytter, Kostas Tsichlas, Costas Iliopoulos, Makris, C., Rytter, Wojciech   +17 more
core  

Numerical cognition in speakers of an Amazonian language with exactly twenty number words. [PDF]

Psychol Res
da Silva Sinha V, Sabino WK, Göbel SM, Majid A.   +3 more
europepmc   +1 more source