Results 71 to 80 of about 902,530 (302)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Approximate Reasoning for Processing Uncertainty

open access: yesJournal of Advanced Computational Intelligence and Intelligent Informatics, 2001
In Bayesian networks as well as in knowledge-based systems, uncertainty in propositions can be represented by various degrees of belief encoded by qualitative values. In this paper, we present a qualitative approach of classical probability theory in the particular case where the set of probability degrees is replaced by a totally ordered set of ...
Hamid Seridi, Herman Akdag
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Causal reasoning in epidemiology: Philosophy and logic

open access: yesGlobal Epidemiology, 2020
This commentary adds to a lively discussion of causal modeling, reasoning and inference in the recent epidemiologic literature. We focus on fundamental philosophical and logical principles of causal reasoning in epidemiology, raising important points not
George Maldonado, Louis Anthony Cox
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Truth Degrees Theory and Approximate Reasoning in 3-Valued Propositional Pre-Rough Logic

open access: yesJournal of Applied Mathematics, 2013
By means of the function induced by a logical formula A, the concept of truth degree of the logical formula A is introduced in the 3-valued pre-rough logic in this paper.
Yingcang Ma, Juanjuan Zhang, Huan Liu
doaj   +1 more source

Visual Form Perception Can Be a Cognitive Correlate of Lower Level Math Categories for Teenagers

open access: yesFrontiers in Psychology, 2017
Numerous studies have assessed the cognitive correlates of performance in mathematics, but little research has been conducted to systematically examine the relations between visual perception as the starting point of visuospatial processing and typical ...
Jiaxin Cui   +5 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Development of an optimal spatial decision-making system using approximate reasoning [PDF]

open access: yes, 2005
There is a recognised need for the continued improvement of both the techniques and technology for spatial decision support in infrastructure site selection.
Bailey, David Thomas
core  

Modeling evaluation of the size of countries (regions) using fuzzy logic [PDF]

open access: yesGeographica Pannonica, 2010
Countries (regions) size rating is based on various parameters: area, population, population density, economic development (GDP, GDP per capita etc.), natural resources, markets, etc. The most common rating is based on the area of the country (km2).
Stojić Gordan   +4 more
doaj  

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