Results 81 to 90 of about 902,530 (302)
Genetic Fuzzy System for Financial Management
Cybernetics and Information Technologies, 2018 This paper discusses genetic fuzzy systems – hybrid systems of artificial intelligence combining the potential of fuzzy sets for modeling approximate reasoning with the abilities of genetic algorithms for finding optimal solutions.
Georgieva Penka V.
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
A Case Based Reasoning System for Automated Forensic Examinations [PDF]
, 2011 While still relatively young the use of digital forensics in criminal investigations is increasing. This hasprompted law enforcement agencies to look at developing more efficient techniques for investigating digital media.
Vickers, Paul +3 more
core
Belief-Logic Conflict Resolution in Syllogistic Reasoning: Inspection-Time Evidence for a Parallel-Process Model [PDF]
, 2008 An experiment is reported examining dual-process models of belief bias in syllogistic reasoning using a problem complexity manipulation and an inspection-time method to monitor processing latencies for premises and conclusions.
Stupple, Edward J. N. +3 more
core +1 more source
Regulation of water resources systems using fuzzy logic: a case study of Amaravathi dam
Applied Water Science, 2018 Regulation of a water resource system is one of the challenging tasks due to uncertainty involved in demand and supply. It may be due to changes in the climatic conditions, living standards of people, land-use patterns and even because of changes in ...
P. V. P. Moorthi +2 more
doaj +1 more source
Inclusion-Based Approximate Reasoning [PDF]
, 2001 We present a kind of fuzzy reasoning, dependent on a measure of fulfilment of the antecedent clause, that captures all the expressiveness of the traditional approximate reasoning methodology based on the Compositional Rule of Inference (CRI) and at the same time rules out a good deal of its inherent complexity.
Chris Cornelis, Etienne E. Kerre
openaire +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Normative benchmarks are useful for studying individual differences in reasoning [PDF]
, 2011 We applaud many aspects of Elqayam & Evans' (E&E's) call for a descriptivist research programme in studying reasoning. Nevertheless, we contend that normative benchmarks are vital for understanding individual differences in performance. We argue that the
Stupple, Edward J. N. +5 more
core +1 more source