Results 91 to 100 of about 291,463 (261)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A Numerical Solution of Volterra's Population Growth Model Based on Hybrid Function [PDF]

open access: yesInternational Journal Bioautomation, 2017
In this paper, a new numerical method for solving Volterra's population growth model is presented. Volterra's population growth model is a nonlinear integro-differential equation. In this method, by introducing the combination of fourth kind of Chebyshev
Saeid Jahangiri   +2 more
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

A new proof of Borel's lemma in two dimensions

open access: yesElectronic Journal of Differential Equations, 2015
Existence of solutions for nonlinear problems can often be established by a Newton's scheme, near an approximate solution, combined with a regularization procedure.
Dening Li
doaj  

Superconvergence of a finite element method for linear integro-differential problems

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2000
We introduce a new way of approximating initial condition to the semidiscrete finite element method for integro-differential equations using any degree of elements. We obtain several superconvergence results for the error between the approximate solution
Do Y. Kwak, Sungyun Lee, Qian Li
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Generalized Hyers–Ulam stability of mixed-type additive-quartic mappings in 2-Banach spaces

open access: yesDemonstratio Mathematica
This paper aims to explore the stability of a mixed-type additive-quartic functional equation in 2-Banach spaces via the direct method. We categorize mappings satisfying a certain functional inequality into odd, even, and general mappings, and establish ...
Ponmana Selvan Arumugam   +2 more
doaj   +1 more source

Reproducing kernel method for a class of weakly singular Fredholm integral equations

open access: yesJournal of Taibah University for Science, 2018
Numerical methods for solving integral equations have been the focus of much research, including reproducing kernel methods. We present a new algorithm to solve weakly singular Fredholm integral equations (WSFIEs). The advantage of this method is that it
Azizallah Alvandi, Mahmoud Paripour
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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