Results 181 to 190 of about 2,095,948 (338)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Improved initial approximation for errors-in-variables system identification

Errors-in-variables system identification can be posed and solved as a Hankel structured low-rank approximation problem. In this paper different estimates based on suboptimal low-rank approximations are considered.
Usevich, Konstantin
core   +1 more source

Finite-Resolution Information from Collision Statistics. [PDF]

Entropy (Basel)
Gates AJ.
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Approximating prediction error variances and reliabilities in a multiple-trait genomic prediction model using Monte Carlo sampling. [PDF]

Theor Appl Genet
Heikkilä A, Strandén I, Lidauer MH, Nordhausen K, Taskinen S.   +4 more
europepmc   +1 more source

Approximation Concepts for Optimum Structural Design

, 1982
When elastic behaviour is assumed, the optimum structural design problem is stated in an implicit nonlinear programming form. Approximate behaviour models are introduced to obtain explicit constraint functions, essential in many practical design problems.
U. Kirsch
core  

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Fluorescent Analysis of K_M and V_max Values for Methyl-Dependent Restriction Endonucleases. [PDF]

Biomolecules
Martyshova V, Sedykh S.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Equivalent Modeling and Calculation of the Infrared Characteristics of Combined Multi-Regular Triangular Pyramid Cavity Structures Based on Cavity Radiation Theory. [PDF]

Sensors (Basel)
Zhou S, Hu S, Wu H, Luo Y.
europepmc   +1 more source