Results 161 to 170 of about 2,095,948 (338)

Rational Approximation

open access: yesNotices of the American Mathematical Society
Rational approximation has gone through a transformation in recent years with the appearance of algorithms that make computing rational approximations easy. The aim of this short story is not to describe these algorithms, but to show how beautifully they can reveal the power of rational functions and the mathematics of rational approximation.
openaire   +3 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

The Empirical Saddlepoint Approximation for GMM Estimators [PDF]

open access: yes
The empirical saddlepoint distribution provides an approximation to the sampling distributions for the GMM parameter estimates and the statistics that test the overidentifying restrictions.
Sowell, Fallaw
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Nonlocal critical Kirchhoff problems in high dimension

open access: yesElectronic Journal of Differential Equations
We study the nonlocal critical Kirchhoff problem $$\displaylines{ -\Big(a+b\int_\Omega |\nabla u|^2dx\Big)\Delta u =|u|^{2^*-2}u +\lambda f(x,u), \quad \text{in } \Omega,\cr u=0, \quad \text{on } \partial\Omega, }$$ where $\Omega$ is a bounded smooth ...
Giovanni Anello
doaj  

Plate Heat Exchanger Optimization Using Different Approximation Assisted Multiobjective Optimization Techniques [PDF]

open access: yes, 2012
This paper presents a comparison between different multiobjective optimization approaches that can be used to optimize the design of thermal equipment. Plate heat exchanger is taken as case study to apply different optimization techniques.
Aute, Vikrant   +3 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Approximation of Jump Diffusions in Finance and Economics [PDF]

open access: yes
In finance and economics the key dynamics are often specified via stochastic differential equations (SDEs) of jump-diffusion type. The class of jump-diffusion SDEs that admits explicit solutions is rather limited.
Nicola Bruti-Liberati, Eckhard Platen
core  

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