Results 161 to 170 of about 1,062,165 (308)

Chebyshev polynomial approximation to approximate partial differential equations [PDF]

open access: yes
This pa per suggests a simple method based on Chebyshev approximation at Chebyshev nodes to approximate partial differential equations. The methodology simply consists in determining the value function by using a set of nodes and basis functions.
Guglielmo Maria Caporale, Mario Cerrato
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

An Improved Approximation to the Distributions in GMM Estimation [PDF]

open access: yes
The empirical saddlepoint distribution provides an approximation to the sampling distributions for the GMM parameter estimates and the statistics that test the overidentifying restrictions.
Fallaw Sowell
core  

Rational approximation of discrete data with asymptomatic behaviour [PDF]

open access: yes
This thesis is concerned with the least-squares approximation of discrete data that appear to exhibit asymptotic behaviour. In particular, we consider using rational functions as they are able to display a number of types of asymptotic behaviour.
Cooper, Philip
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Structured low-rank approximation with missing data

open access: yes
The approach of SIAM J. Matrix Anal. Appl., 26(4):1083--1099 for solving structured total least squares problems is generalized to weighted structured low-rank approximation with missing data. The method proposed is based on elimination of the correction
Markovsky, Ivan, Usevich, Konstantin
core   +1 more source

Approximating Peak Prevalence in Multistage SIR Epidemics. [PDF]

open access: yesBull Math Biol
Tverskoi D, Gothard A, Rempala GA.
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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