Results 51 to 60 of about 430,873 (249)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Reduction of decision rule of multivariate interpolation and approximation method in the problem of data classification [PDF]

open access: yesКомпьютерные исследования и моделирование, 2016
This article explores a method of machine learning based on the theory of random functions. One of the main problems of this method is that decision rule of a model becomes more complicated as the number of training dataset examples increases.
Ivan Vladimirovich Kopylov
doaj   +1 more source

Approximating Approximate Distance Oracles

open access: yes, 2016
Given a finite metric space $(V,d)$, an approximate distance oracle is a data structure which, when queried on two points $u,v \in V$, returns an approximation to the the actual distance between $u$ and $v$ which is within some bounded stretch factor of the true distance.
Dinitz, Michael, Zhang, Zeyu
openaire   +4 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Methods for the algorithms for calculation of tunable coaxial bandpass microwave filters

open access: yesТехнологія та конструювання в електронній апаратурі, 2012
The article describes the features of the models and algorithms used for calculation of the characteristics of mechanically tunable coaxial bandpass microwave filters, on the basis of which a calculation computer program can be written.
A. A. Parfilov
doaj  

APPLICATION OF THE METHOD OF LINES FOR SOLVING ONE-DIMENSIONAL EQUATION OF PARABOLIC TYPE UNDER THE BOUBDARY CONDITIONS OF THE SECOND AND FIRS GENERA [PDF]

open access: yesVestnik KRAUNC: Fiziko-Matematičeskie Nauki, 2018
In the article an algorithm for solving a one-dimensional inhomogeneous parabolic equation is described under boundary conditions of the second kind at the beginning and of the first kind at the end of the interval. By introduction of a grid with respect
I. K. Karimov   +2 more
doaj   +1 more source

Approximate approximations on nonuniform grids

open access: yesLe Matematiche, 2007
We present an extension of approximate quasi-interpolation on uniformly distributed nodes, to functions given on a set of nodes close to an uniform, not necessarily cubic, grid.
LANZARA, Flavia, V. Maz'ya, G. Schmidt
openaire   +2 more sources

Positive Approximants [PDF]

open access: yesTransactions of the American Mathematical Society, 1973
Let T = B + i C T = B + iC with B = B ∗ , C = C ∗ B = {B^\ast },C = {C^\ast } and let δ ( T )
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy