Results 81 to 90 of about 430,873 (249)

Two new classes of compactly supported radial basis functions for approximation of discrete and continuous data

Engineering Reports, 2019
Radial basis functions (RBFs), first proposed for interpolation of scattered data, have gotten the scientific community interest in the past two decades, with applications ranging from interpolation with the dual reciprocity approach of the boundary ...
Fernando César Meira Menandro
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

PREDICTION OF TITANIUM ALLOYS EROSIVE WEAR UNDER LONG-TERM DROPLET-IMPACT EFFECT

Advanced Engineering Research, 2011
The approximating model for the definition of the steam turbines blades wear rate under the continuous operation through the droplet-impact erosion is built on the ground of the comparative analysis of the stand test data of the titanium alloy samples.
Valery N. Varavka, Oleg V. Kudryakov, Alexey F. Mednikov   +2 more
doaj  

Approximation of Any Particle Size Distribution Employing a Bidisperse One Based on Moment Matching

Colloids and Interfaces
Dispersed phases like colloidal particles and emulsions are characterized by their particle size distribution. Narrow distributions can be represented by the monodisperse distribution. However, this is not the case for broader distributions.
Margaritis Kostoglou, Thodoris D. Karapantsios   +1 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Accelerated Modeling of Transients in Electromagnetic Devices Based on Magnetoelectric Substitution Circuits

Energies
During switching in electrical systems, transient electromagnetic processes occur. The resulting dangerous current surges are best studied by computer simulation.
Sergii Tykhovod, Ihor Orlovskyi
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

FEATURES OF USE OF MONTE-CARLO METHOD FOR APPROXIMATION OF STATISTICAL DISTRIBUTIONS OF RESULTS OF NONLINEAR TRANSFORMATIONS IN RADAR-TRACKING PROBLEMS

Весці Нацыянальнай акадэміі навук Беларусі: Серыя фізіка-тэхнічных навук, 2017
An approach to the decision of mathematical problems with use of modelling random variables, the method which has received the name of Monte-Carlo is considered. The given method has got the greatest popularity for numerical calculation of high frequency
A. S. Solonar, S. N. Yarmolik, A. S. Khramenkov, A. A. Mikhalkovski   +3 more
doaj  

Systems of Approximating Functions when Using Variational Methods for Calculating Thin-Walled Building Structures

Structural Mechanics of Engineering Constructions and Buildings
The question of the use of approximating functions in the calculation of thinwalled building structures is investigated and the requirements that they must satisfy are analyzed.
Vladimir V. Karpov
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source