Results 111 to 120 of about 1,003,970 (287)
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Fast approximation algorithms for some maximin clustering problems [PDF]
Yugoslav Journal of Operations ResearchIn this paper, we consider three cases of an intractable problem of searching for two subsets in a finite set of points of Euclidean space. In all three cases, it is required to maximize the minimum cluster’s cardinality under constraint on each cluster ...
Khandeev V., Neshchadim S.
doaj +1 more source
An improved approximation algorithm for the reversal and transposition distance considering gene order and intergenic sizes. [PDF]
Algorithms Mol Biol, 2021 Brito KL +4 more
europepmc +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Algorithm of Quasiuniform Filling of Reachable Set for Nonlinear Control System
Известия Иркутского государственного университета: Серия "Математика", 2017 In this paper, we propose an algorithm of obtaining points that uniformly fill the volume of the reachable set, and even for a small number of elements results in a cloud quasiuniform approximation of the set. To solve the task of finding each additional
E. Finkelstein, A. Gornov
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source
Approximation for Batching via Priorities [PDF]
Scientific Annals of Computer Science, 2007 We consider here the one-machine serial batching problem under weighted average completion. This problem is known to be $cal Ncal P$-hard and no good approximation algorithms are known. Batching has wide application in manufacturing, decision management,
W. Bein, J. Noga, J. Wiegley
doaj
A Fast, Provably Accurate Approximation Algorithm for Sparse Principal Component Analysis Reveals Human Genetic Variation Across the World. [PDF]
Res Comput Mol Biol, 2022 Chowdhury A +4 more
europepmc +1 more source
Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
Applied SciencesMobile edge computing (MEC), specifically wireless powered mobile edge computing (WPMEC), can achieve superior real-time data analysis and intelligent processing.
Ming Lei, Zhe Fu, Bocheng Yu
doaj +1 more source