Results 91 to 100 of about 138,670 (265)

Approximation algorithm for rearrangement distances considering repeated genes and intergenic regions. [PDF]

Algorithms Mol Biol, 2021
Siqueira G, Alexandrino AO, Oliveira AR, Dias Z.   +3 more
europepmc   +1 more source

Approximation Algorithms for Noncommutative CSPs [PDF]

2024 IEEE 65th Annual Symposium on Foundations of Computer Science (FOCS)
74 pages, 8 figures, revisions targeting only the clarity of the ...
Culf, Eric, Mousavi, Hamoon, Spirig, Taro Johann   +2 more
openaire   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

An improved approximation algorithm for the reversal and transposition distance considering gene order and intergenic sizes. [PDF]

Algorithms Mol Biol, 2021
Brito KL, Oliveira AR, Alexandrino AO, Dias U, Dias Z.   +4 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

A Fast, Provably Accurate Approximation Algorithm for Sparse Principal Component Analysis Reveals Human Genetic Variation Across the World. [PDF]

Res Comput Mol Biol, 2022
Chowdhury A, Bose A, Zhou S, Woodruff DP, Drineas P.   +4 more
europepmc   +1 more source

Approximation Algorithms for Domination Search

, 2011
The r-domination search game on graphs is a game-theoretical approach to the investigation of several graph and hypergraph parameters including treewidth and hypertree width. The task is to identify the minimum number of cops sufficient to catch the visible and fast robber.
Fedor V. Fomin, Petr A. Golovach, Dimitrios M. Thilikos   +2 more
openaire   +2 more sources

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Detect Key Gene Information in Classification of Microarray Data

EURASIP Journal on Advances in Signal Processing, 2008
We detect key information of high-dimensional microarray profiles based on wavelet analysis and genetic algorithm. Firstly, wavelet transform is employed to extract approximation coefficients at 2nd level, which remove noise and reduce dimensionality ...
Yihui Liu
doaj   +1 more source