Results 71 to 80 of about 138,670 (265)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
On Pseudodeterministic Approximation Algorithms.
, 2018 We investigate the notion of pseudodeterminstic approximation algorithms. A randomized approximation algorithm A for a function f is pseudodeterministic if for every input x there is a unique value v so that A(x) outputs v with high probability, and v is a good approximation of f(x).
Peter Dixon 0002 +2 more
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Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Cybernetics and Information Technologies, 2019 Choice Based Course Selection (CBCS) allows students to select courses based on their preferred sequence. This preference in selection is normally bounded by constraints set by a university like pre-requisite(s), minimum and maximum number of credits ...
Premalatha M., Viswanathan V.
doaj +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Remote SensingOver the past few decades, there has been a significant increase in the number of Earth observation satellites, and the area of ground targets requiring observation has also been expanding.
Feng Li +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Distances Between Phylogenetic Trees: A Survey
Tsinghua Science and Technology, 2013 Phylogenetic trees have been widely used in the study of evolutionary biology for representing the tree-like evolution of a collection of species. However, different data sets and different methods often lead to the construction of different phylogenetic
Feng Shi +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Approximation algorithms for spreading points
Journal of Algorithms, 2005 We consider the problem of placing n points, each one inside its own, prespecified disk, with the objective of maximizing the distance between the closest pair of them. The disks can overlap and have different sizes. The problem is NP-hard and does not admit a PTAS. In the L∞ metric, we give a 2-approximation algorithm running in $O(n{\sqrt n}log^{2}n)$
openaire +2 more sources