Results 71 to 80 of about 2,913,313 (303)
An Approximation Algorithm for the MAX-2-Local Hamiltonian Problem [PDF]
, 2020 We present a classical approximation algorithm for the MAX-2-Local Hamiltonian problem. This is a maximization version of the QMA-complete 2-Local Hamiltonian problem in quantum computing, with the additional assumption that each local term is positive ...
Lee, Eunou, Parekh, Ojas, Hallgren, Sean
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A Novel Method of Offset Approximation along the Normal Direction with High Precision
Mathematical and Computational Applications, 2017 A new algorithm is proposed for polynomial or rational approximation of the planar offset curve. The best rational Chebyshev approximation could be regarded as a kind of geometric approximation along the fixed direction.
Hongyan Zhao, Lian Zhou
doaj +1 more source
Approximation Algorithms for Movement Repairmen [PDF]
ACM Transactions on Algorithms, 2013 In the Movement Repairmen (MR) problem, we are given a metric space ( V , d ) along with a set R of k repairmen r
MohammadTaghi Hajiaghayi +3 more
openaire +2 more sources
A Greedy Algorithm for Subspace Approximation Problem [PDF]
, 2018 In the subspace approximation problem, given m points in R^{n} and an integer k
Thang, Nguyen Kim
core +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Clustering Affine Subspaces: Algorithms and Hardness [PDF]
, 2012 We study a generalization of the famous k-center problem where each object is an affine subspace of dimension Δ, and give either the first or significantly improved algorithms and hardness results for many combinations of parameters.
Lee, Euiwoong
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
A 3/2-Approximation Algorithm for the Graph Balancing Problem with Two Weights
Algorithms, 2016 In the pursuit of finding subclasses of the makespan minimization problem on unrelated parallel machines that have approximation algorithms with approximation ratio better than 2, the graph balancing problem has been of current interest.
Daniel R. Page, Roberto Solis-Oba
doaj +1 more source