Results 81 to 90 of about 1,003,970 (287)

Distributed Approximation of Maximum Independent Set and Maximum Matching

, 2017
We present a simple distributed $\Delta$-approximation algorithm for maximum weight independent set (MaxIS) in the $\mathsf{CONGEST}$ model which completes in $O(\texttt{MIS}(G)\cdot \log W)$ rounds, where $\Delta$ is the maximum degree, $\texttt{MIS}(G)$
Bar-Yehuda Reuven, Bodlaender Marijke HL, Czygrinow Andrzej, Edmonds Jack, Halldórsson Magnús M, Kuhn Fabian   +5 more
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

An improved Alpha approximation algorithm for time-series surface soil moisture inversion from Sentinel-1 SAR data

International Journal of Applied Earth Observations and Geoinformation
Accurate measurement of soil moisture content has significant scientific value and social benefits for studying global or regional water cycle mechanisms, developing climate and hydrological models, and advancing sustainable agricultural development. The
Leilei Dong, Tao Che, Xin Huang, Xingze Li, Haining Wei, Feinan Xu, Weizhen Wang   +6 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Course Sequence Recommendation with Course Difficulty Index Using Subset Sum Approximation Algorithms

Cybernetics and Information Technologies, 2019
Choice Based Course Selection (CBCS) allows students to select courses based on their preferred sequence. This preference in selection is normally bounded by constraints set by a university like pre-requisite(s), minimum and maximum number of credits ...
Premalatha M., Viswanathan V.
doaj   +1 more source

On Pseudodeterministic Approximation Algorithms.

, 2018
We investigate the notion of pseudodeterminstic approximation algorithms. A randomized approximation algorithm A for a function f is pseudodeterministic if for every input x there is a unique value v so that A(x) outputs v with high probability, and v is a good approximation of f(x).
Dixon, Peter, Pavan, A., Vinodchandran, N. V.   +2 more
openaire   +3 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Multi-Satellite Imaging Task Planning for Large Regional Coverage: A Heuristic Algorithm Based on Triple Grids Method

Remote Sensing
Over the past few decades, there has been a significant increase in the number of Earth observation satellites, and the area of ground targets requiring observation has also been expanding.
Feng Li, Qiuhua Wan, Feifei Wen, Yongkui Zou, Qien He, Da Li, Xing Zhong   +6 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source