Results 41 to 50 of about 85,241 (257)
Two-Layer Network Caching for Different Service Requirements
Future Internet, 2021 Network caching is a technique used to speed-up user access to frequently requested contents in complex data networks. This paper presents a two-layer overlay network caching system for content distribution.
Gianluca Reali, Mauro Femminella
doaj +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Bamboo Garden Trimming Problem: Priority Schedulings
Algorithms, 2019 The paper deals with the Bamboo Garden Trimming (BGT) problem introduced in [Gąsieniec et al., SOFSEM’17]. The problem is difficult to solved due to its close relationship to Pinwheel scheduling. The garden with n bamboos is an analogue of a system
Mattia D’Emidio +2 more
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All-norm approximation algorithms [PDF]
Journal of Algorithms, 2002 Summary: A major drawback in optimization problems and in particular in scheduling problems is that for every measure there may be a different optimal solution. In many cases the various measures are different \(\ell_p\) norms. We address this problem by introducing the concept of an all-norm \(\rho\)-approximation algorithm, which supplies one ...
Azar, Yossi +3 more
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Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Efficient Subspace Approximation Algorithms [PDF]
Discrete & Computational Geometry, 2011 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Shyamalkumar, Nariankadu D. +1 more
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Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Efficient Algorithms for Coded Multicasting in Heterogeneous Caching Networks
Entropy, 2019 Coded multicasting has been shown to be a promising approach to significantly improve the performance of content delivery networks with multiple caches downstream of a common multicast link.
Giuseppe Vettigli +5 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source