Results 51 to 60 of about 129,306 (313)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Two Approaches to Constructing Certified Dominating Sets in Social Networks
IEEE AccessSocial networks are an important part of our community. In this context, certified dominating sets help to find in networks a group of people, referring as officials, such that 1) for each civilian, there is an official that can serve the civilian, and 2)
Joanna Raczek, Mateusz Miotk
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Fast Approximation Algorithms for Bounded Degree and Crossing Spanning Tree Problems [PDF]
, 2021 We develop fast approximation algorithms for the minimum-cost version of the Bounded-Degree MST problem (BD-MST) and its generalization the Crossing Spanning Tree problem (Crossing-ST). We solve the underlying LP to within a (1+ε) approximation factor in
Torres, Manuel R. +2 more
core +1 more source
Reachability in Biochemical Dynamical Systems by Quantitative Discrete Approximation (extended abstract) [PDF]
Electronic Proceedings in Theoretical Computer Science, 2011 In this paper, a novel computational technique for finite discrete approximation of continuous dynamical systems suitable for a significant class of biochemical dynamical systems is introduced.
L. Brim +3 more
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Mildly Exponential Time Approximation Algorithms for Vertex Cover, Balanced Separator and Uniform Sparsest Cut [PDF]
, 2018 In this work, we study the trade-off between the running time of approximation algorithms and their approximation guarantees. By leveraging a structure of the "hard" instances of the Arora-Rao-Vazirani lemma [Sanjeev Arora et al., 2009; James R.
Trevisan, Luca, Manurangsi, Pasin
core +1 more source
Bamboo Garden Trimming Problem: Priority Schedulings
Algorithms, 2019 The paper deals with the Bamboo Garden Trimming (BGT) problem introduced in [Gąsieniec et al., SOFSEM’17]. The problem is difficult to solved due to its close relationship to Pinwheel scheduling. The garden with n bamboos is an analogue of a system
Mattia D’Emidio +2 more
doaj +1 more source
Two-Layer Network Caching for Different Service Requirements
Future Internet, 2021 Network caching is a technique used to speed-up user access to frequently requested contents in complex data networks. This paper presents a two-layer overlay network caching system for content distribution.
Gianluca Reali, Mauro Femminella
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source