Results 71 to 80 of about 129,306 (313)

Exact and Approximation Algorithms for Clustering [PDF]

Algorithmica, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Pankaj K. Agarwal, Cecilia Magdalena Procopiuc   +1 more
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

09511 Abstracts Collection – Parameterized complexity and approximation algorithms [PDF]

, 2010
From 14. 12. 2009 to 17. 12. 2009., the Dagstuhl Seminar 09511 ``Parameterized complexity and approximation algorithms '' was held in Schloss Dagstuhl~--~Leibniz Center for Informatics.
Marx, Dániel, Hajiaghayi, MohammadTaghi, Demaine, Erik D.   +2 more
core   +1 more source

A New Modification of Baskakov–Schurer–Stancu Operators: Weighted and Pointwise Approximation Theories

Mathematics
The behavior of a new modification of operators of the Baskakov–Schurer–Stancu variant is discussed in this study. First, we establish certain necessary moment and central moment estimates.
Nadire Fulda Odabaşı, Mohammad Farid, Nadeem Rao, Reşat Aslan   +3 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Parameterized Approximation Algorithms for TSP [PDF]

, 2022
We study the Traveling Salesman problem (TSP), where given a complete undirected graph G = (V,E) with n vertices and an edge cost function c:E↦R_{⩾0}, the goal is to find a minimum-cost cycle visiting every vertex exactly once.
Guo, Jiong, Zhou, Jianqi, Li, Peihua
core   +1 more source

Scheduling Non-Preemptible Jobs to Minimize Peak Demand

Algorithms, 2017
This paper examines an important problem in smart grid energy scheduling; peaks in power demand are proportionally more expensive to generate and provision for. The issue is exacerbated in local microgrids that do not benefit from the aggregate smoothing
Sean Yaw, Brendan Mumey
doaj   +1 more source

Approximation algorithms for stochastic clustering

J. Mach. Learn. Res., 2018
We consider stochastic settings for clustering, and develop provably-good approximation algorithms for a number of these notions. These algorithms yield better approximation ratios compared to the usual deterministic clustering setting. Additionally, they offer a number of advantages including clustering which is fairer and has better long-term ...
David G. Harris 0001, Shi Li 0001, Aravind Srinivasan, Khoa Trinh, Thomas W. Pensyl   +4 more
openaire   +5 more sources

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Approximation methods for hybrid diffusion systems with state-dependent switching processes : numerical algorithms and existence and uniqueness of solutions

, 2010
By focusing on hybrid diffusions in which continuous dynamics and discrete events coexist, this work is concerned with approximation of solutions for hybrid stochastic differential equations with a state-dependent switching process.
Yuan, Chenggui, Yuan, C., Yin, G., Mao, X., Chenggui Yuan, Cao, D., Mao, Xuerong, Cao, Dingzhou   +7 more
core   +1 more source