Results 81 to 90 of about 129,306 (313)
Efficient Approximation for Restricted Biclique Cover Problems
Algorithms, 2018 Covering the edges of a bipartite graph by a minimum set of bipartite complete graphs (bicliques) is a basic graph theoretic problem, with numerous applications. In particular, it is used to characterize parsimonious models of a set of observations (each
Alessandro Epasto, Eli Upfal
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
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Adding Edges for Maximizing Weighted Reachability
Algorithms, 2020 In this paper, we consider the problem of improving the reachability of a graph. We approach the problem from a graph augmentation perspective, in which a limited set size of edges is added to the graph to increase the overall number of reachable nodes ...
Federico Corò +2 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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Mathematics, 2020 We investigate the Pareto-scheduling problem with two competing agents on a single machine to minimize the total weighted completion time of agent A’s jobs and the total weighted late work of agent B’s jobs, the B-jobs having a common due date.
Yuan Zhang, Zhichao Geng, Jinjiang Yuan
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Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Almost Optimal Classical Approximation Algorithms for a Quantum Generalization of Max-Cut [PDF]
, 2019 Approximation algorithms for constraint satisfaction problems (CSPs) are a central direction of study in theoretical computer science. In this work, we study classical product state approximation algorithms for a physically motivated quantum ...
Parekh, Ojas, Gharibian, Sevag
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Electrical, Control and Communication Engineering, 2014 In this paper the electromechanical battery (EMB) with synchronous machine is described. Theoretically, if electrical machines rotor stored energy is known, it is possible to reduce the flywheel mass of electromechanical battery.
Podgornovs Andrejs, Sipovichs Antons
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Pade Method for Construction of Numerical Algorithms for Fractional Initial Value Problem
Journal of Mathematics, 2020 In this paper, we propose an efficient method for constructing numerical algorithms for solving the fractional initial value problem by using the Pade approximation of fractional derivative operators. We regard the Grunwald–Letnikov fractional derivative
Feng Gao, Chunmei Chi
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Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
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