Results 91 to 100 of about 545,451 (275)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Exponential series approximation of the SIR epidemiological model

Frontiers in Physics
IntroductionThe SIR (Susceptible-Infected-Recovered) model is one of the simplest and most widely used frameworks for understanding epidemic outbreaks.MethodsA second-order dynamical system for the R variable is formulated using an infinite exponential ...
Dimiter Prodanov, Dimiter Prodanov
doaj   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

A kernel method for non-linear systems indentification - infinite degree volerra series estimation [PDF]

Volterra series expansions are widely used in analyzing and solving the problems of non-linear dynamical systems. However, the problem that the number of terms to be determined increases exponentially with the order of the expansion restricts its ...
Dodd, T.J., Harrison, R.F., Wan, Y.
core  

Higher Order Corrections to the Primordial Gravitational Wave Spectrum and its Impact on Parameter Estimates for Inflation

, 2011
We study the impact of the use of the power series expression for the primordial tensor spectrum on parameter estimation from future direct detection gravitational wave experiments.
A.A. Starobinsky, A.D. Linde, C. Caprini, C. Ungarelli, E. Fenu, J. Martin, J.-F. Dufaux, K. Jedamzik, K. Nakayama, K. Nakayama, K. Sato, M. Kawasaki, P. Adshead, Planck collaboration, R. Easther, S. Kawamura ., S. Phinney ., Sachiko Kuroyanagi, T. Hiramatsu, T. Suyama, T. Suyama, T.C. collaboration, Tomo Takahashi, V. Corbin, WMAP collaboration, Y. Suwa   +25 more
core   +1 more source

A Memory–Efficient Noninteger–Order Discrete–Time State–Space Model of a Heat Transfer Process

International Journal of Applied Mathematics and Computer Science, 2018
A new, state space, discrete-time, and memory-efficient model of a one-dimensional heat transfer process is proposed. The model is derived directly from a time-continuous, state-space semigroup one.
Oprzędkiewicz Krzysztof, Mitkowski Wojciech   +1 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

A Fuzzy Fractional Power Series Approximation and Taylor Expansion for Solving Fuzzy Fractional Differential Equation

Decision Analytics Journal
Fuzzy fractional differential has the strength to capture the senses of memory and uncertainty simultaneously involved in dynamical systems. However, a solution for fuzzy fractional differential equations is not always found regularly. This paper discusses a numerical solution approach for the fuzzy fractional differential equation using power series ...
Payal Singh, Kamal Hossain Gazi, Mostafijur Rahaman, Soheil Salahshour, Sankar Prasad Mondal   +4 more
openaire   +2 more sources

Comparison of the methods for discrete approximation of the fractional-order operator [PDF]

Acta Montanistica Slovaca, 2003
In this paper we will present some alternative types of discretization methods (discrete approximation) for the fractional-order (FO) differentiator and their application to the FO dynamical system described by the FO differential equation (FDE).
Zborovjan Martin, Terpák Ján, PetrᚠIvo, Dorèák ¼ubomír   +3 more
doaj  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source