Results 51 to 60 of about 9,593 (216)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

\(A\)-statistical convergence for a class of positive linear operators

Journal of Numerical Analysis and Approximation Theory, 2006
In this paper we introduce a sequence of positive linear operators defined on the space \(C[0,a ...
M. A. Özarslan, O. Duman, O. Doğru
doaj   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Durrmeyer-Stancu type operators

Journal of Numerical Analysis and Approximation Theory, 2010
Considering two given real parameters \(\alpha, \beta\) satisfying the conditions \(0\leq\alpha\leq\beta\), D. D. Stancu [7] constructed and studied the linear positive operators \(P^{(\alpha,\beta)}_m:C([0,1])\to C([0,1])\), defined for any \(f\in C([0 ...
Ovidiu T. Pop, Dan Bărbosu
doaj   +2 more sources

Integral Modification of Lupaş-Type Operators for Improved Approximation and Reduced Bias

Journal of Function Spaces
In this paper, we introduce a generalized class of Lupaş-type operators constructed through an integral modification of the classical formulation. Instead of using discrete point evaluations, the proposed operators are defined by means of weighted local ...
Nadiyah Hussain Alharthi, Mehmet Zeki Sarıkaya, Rubayyi T. Alqahtani   +2 more
doaj   +1 more source

Projective tensor products of approximation spaces associated with positive operators

Researches in Mathematics
In this paper the projective tensor products of approximation spaces associated with positive operators in Banach spaces are characterized. We show that the tensor products of approximation spaces can be considered as the interpolation spaces generated ...
M.I. Dmytryshyn, L.I. Dmytryshyn
doaj   +1 more source

Multivariate and abstract approximation theory for Banach space valued functions

Demonstratio Mathematica, 2017
Here we study quantitatively the high degree of approximation of sequences of linear operators acting on Banach space valued Fréchet differentiable functions to the unit operator, as well as other basic approximations including those under convexity ...
Anastassiou George A.
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source