Results 71 to 80 of about 57,996,643 (272)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Durrmeyer-Stancu type operators

Journal of Numerical Analysis and Approximation Theory, 2010
Considering two given real parameters \(\alpha, \beta\) satisfying the conditions \(0\leq\alpha\leq\beta\), D. D. Stancu [7] constructed and studied the linear positive operators \(P^{(\alpha,\beta)}_m:C([0,1])\to C([0,1])\), defined for any \(f\in C([0 ...
Ovidiu T. Pop, Dan Bărbosu
doaj   +2 more sources

Projective tensor products of approximation spaces associated with positive operators

Researches in Mathematics
In this paper the projective tensor products of approximation spaces associated with positive operators in Banach spaces are characterized. We show that the tensor products of approximation spaces can be considered as the interpolation spaces generated ...
M.I. Dmytryshyn, L.I. Dmytryshyn
doaj   +1 more source

Multivariate and abstract approximation theory for Banach space valued functions

Demonstratio Mathematica, 2017
Here we study quantitatively the high degree of approximation of sequences of linear operators acting on Banach space valued Fréchet differentiable functions to the unit operator, as well as other basic approximations including those under convexity ...
Anastassiou George A.
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Quantitative estimates for Lp approximation with positive linear operators [PDF]

, 1983
Quantitative estimates for approximation with positive linear operators are derived. The results are in the same vein as recent results of Berens and DeVore.
Swetits, J. J., Wood, B, Wood, B., Swetits, J.J   +3 more
core   +1 more source

Integral Modification of Lupaş-Type Operators for Improved Approximation and Reduced Bias

Journal of Function Spaces
In this paper, we introduce a generalized class of Lupaş-type operators constructed through an integral modification of the classical formulation. Instead of using discrete point evaluations, the proposed operators are defined by means of weighted local ...
Nadiyah Hussain Alharthi, Mehmet Zeki Sarıkaya, Rubayyi T. Alqahtani   +2 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source