Results 91 to 100 of about 1,726,292 (286)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Automated scheme for linearisation points selection in TPWL method applied to non-linear circuits
The Journal of Engineering, 2019 Trajectory piecewise linear (TPWL) approximation is a well-known model order reduction technique for non-linear systems. It involves weighted summation of the dimensionally reduced linear systems obtained at certain points on the system trajectory.
Shifali Kalra, Mashuq-un Nabi
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Multiparameter extrapolation and deflation methods for solving equation systems
International Journal of Mathematics and Mathematical Sciences, 1984 Most models in economics and the applied sciences are solved by first order iterative techniques, usually those based on the Gauss-Seidel algorithm.
A. J. Hughes Hallett
doaj +1 more source
Distributed equalisation strategy for multi-battery energy storage systems
The Journal of Engineering, 2019 Multi-battery energy storage systems (MBESSs) are widely adopted to overcome the uncertainty problem of renewable energy sources. However, state-of-charge (SOC) imbalance issue of MBESSs brings great challenges to the optimal dispatching strategy and the
Feilong Fan +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Sequential optimisation of orthogonal waveforms for MIMO radar
The Journal of Engineering, 2019 The existing methods to design orthogonal waveforms for multiple-input multiple-output radar mainly focus on the optimisation of autocorrelation and cross-correlation properties.
Zhongrui Huang, Bo Tang, Shuo Zhang
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
The Journal of Engineering, 2019 In order to study the fast calculation method of a surface electric field of the arbitrary-quantity bundled conductor and a ground nominal electric field of the HVDC transmission line on slope terrain.
Chenguang Gao +6 more
doaj +1 more source