Results 91 to 100 of about 1,733,746 (287)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Probability constrained optimisation model for transmission expansion planning considering the curtailment of wind power

open access: yesThe Journal of Engineering, 2019
The curtailment of wind power has caused huge economic losses and needs to be considered on the stage of transmission expansion planning (TEP). Based on the superquantile theory, the authors use the buffered failure probability to handle the events of ...
Dundun Liu   +5 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Simplified LLR algorithm for m-QAM demodulation

open access: yesThe Journal of Engineering, 2019
Here, a simplified algorithm to calculate log-likelihood ratio (LLR) for m-QAM demodulation is proposed. Traditional method calculating LLR for m-QAM demodulation is supposed to do distance computing between any two constellation points so that the high ...
Xianle Cao, Yi Liu, Dongfang Hu
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Automated scheme for linearisation points selection in TPWL method applied to non-linear circuits

open access: yesThe Journal of Engineering, 2019
Trajectory piecewise linear (TPWL) approximation is a well-known model order reduction technique for non-linear systems. It involves weighted summation of the dimensionally reduced linear systems obtained at certain points on the system trajectory.
Shifali Kalra, Mashuq-un Nabi
doaj   +1 more source

Approximations of theories

open access: yesSibirskie Elektronnye Matematicheskie Izvestiya, 2020
We study approximations of theories both in general context and with respect to some natural classes of theories. Some kinds of approximations are considered, connections with finitely axiomatizable theories and minimal generating sets of theories as well as their $e$-spectra are found.
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Continuum nuclear structure of O16 in the Eigenchannel reaction theory [PDF]

open access: yes, 2006
The total particle-particle SJ matrix of O16 for spin J=1- and excitation energies between 15 and 27 MeV has been calculated in the eigenchannel reaction theory for several parameters of the Saxon-Woods potential and the two-body force.
Danos, Michael   +2 more
core  

Home - About - Disclaimer - Privacy