Results 71 to 80 of about 791,635 (286)

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Researches on the problem of link disjoint paths pair with QoS constraints

Tongxin xuebao, 2006
The problem of link disjoint paths pair with QoS constraints was discussed.Two routing models about link dis-joint optimal paths pair with QoS constraints were constructed.First it proved that the problem of link disjoint paths pair in the undirected ...
ZHANG Pin 1, ZHANG Jian-wu1, LI Le-min 2, WANG Sheng2   +3 more
doaj   +2 more sources

STABILITY OF MOTION OF RAILWAY VEHICLES DESCRIBED WITH LAGRANGE EQUATIONS OF THE FIRST KIND

Nauka ta progres transportu, 2018
Purpose. The article aims to estimate the stability of the railway vehicle motion, whose oscillations are described by Lagrange equations of the first kind under the assumption that there are no nonlinearities with discontinuities of the right-hand sides.
A. G. Reidemeister, S. I. Levytska
doaj   +1 more source

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew, Maryam Kargaran, Maik Rothe, Andreas Deistung, Dietrich Stoevesandt, Walter A. Wohlgemuth, David Strube, Thomas Kendzierski, Anna Katharina Kölsch, Maurits Gerhard Abraham Heuschen, Markus Otto, Alexander Mensch   +11 more
wiley   +1 more source

Line Integral Solution of Hamiltonian Systems with Holonomic Constraints

, 2017
In this paper, we propose a second-order energy-conserving approximation procedure for Hamiltonian systems with holonomic constraints. The derivation of the procedure relies on the use of the so-called line integral framework.
Brugnano, Luigi, Gurioli, Gianmarco, Iavernaro, Felice, Weinmueller, Ewa B.   +3 more
core   +1 more source

Finite-Dimensional Gaussian Approximation with Linear Inequality Constraints [PDF]

SIAM/ASA Journal on Uncertainty Quantification, 2018
Introducing inequality constraints in Gaussian process (GP) models can lead to more realistic uncertainties in learning a great variety of real-world problems. We consider the finite-dimensional Gaussian approach from Maatouk and Bay (2017) which can satisfy inequality conditions everywhere (either boundedness, monotonicity or convexity).
López-Lopera, Andrés F., Bachoc, François, Durrande, Nicolas, Roustant, Olivier   +3 more
openaire   +4 more sources

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

A cost function approximation method for dynamic vehicle routing with docking and LIFO constraints

Multimodal Transportation
In this paper, we study a dynamic pickup and delivery problem with docking constraints. There is a homogeneous fleet of vehicles to serve pickup-and-delivery requests at given locations.
Markó Horváth, Tamás Kis, Péter Györgyi   +2 more
doaj   +1 more source

New Integrality Gap Results for the Firefighters Problem on Trees

, 2016
The firefighter problem is NP-hard and admits a $(1-1/e)$ approximation based on rounding the canonical LP. In this paper, we first show a matching integrality gap of $(1-1/e+\epsilon)$ on the canonical LP.
Chalermsook, Parinya, Vaz, Daniel
core   +2 more sources