Results 101 to 110 of about 1,914,713 (386)
TP53 is the most frequently mutated gene in cancer. The p53 protein activates transcription of genes that promote cell cycle arrest or apoptosis, or regulate cell metabolism, and other processes. Missense mutations in TP53 abolish specific DNA binding of
V. Bykov +5 more
semanticscholar +1 more source
An Equilibrium Model of Lumpy Housing Investment [PDF]
We formulate and solve a dynamic general equilibrium model with heterogeneous agents and lumpy housing adjustment at the household level. We use the model to ask a simple question: how does the microeconomic lumpiness of housing adjustment affect the ...
Marina Pavan, Matteo Iacoviello
core
Objective Relapsing polychondritis (RP) is a rare disease defined by recurrent cartilaginous inflammation. Anti–collagen II (Col2) antibodies have been proposed as a diagnostic biomarker for RP, but their performance characteristics are not well defined.
Karyssa Stonick +6 more
wiley +1 more source
An open-label phase I dose-finding study of APR-246 in hematological malignancies
Mutations in the TP53 tumor suppressor gene occur at different frequencies in a variety of human malignancies. 1 TP53 encodes a DNA-binding transcription factor that induces cell growth arrest, senescence and cell death by apoptosis upon cellular stress,
Stefan Deneberg +7 more
semanticscholar +1 more source
Objective We developed a novel EHR sidecar application to visualize key rheumatoid arthritis (RA) outcomes, including disease activity, physical function, and pain, via a patient‐facing graphical interface designed for use during outpatient visits (“RA PRO dashboard”).
Gabriela Schmajuk +16 more
wiley +1 more source
Effects of an antler point restriction on deer hunter perceptions and satisfaction in Missouri
Antler point restrictions (APR), intended to create an older male age structure of white‐tailed deer (Odocoileus virginianus), have been implemented in many states, but effects of APR on hunters’ satisfaction and activities often have not been measured ...
Lonnie P. Hansen +5 more
doaj +1 more source
Helping Consumers to Evaluate Annual Percentage Rates (APR) on Credit Cards
To help consumers make informed decisions, regulators often impose disclosure requirements on financial institutions. However, disclosures may not be informative for consumers if they contain difficult-to-evaluate attributes, such as annual percentage ...
Alycia Chin, W. Bruine de Bruin
semanticscholar +1 more source
Direct and Indirect Complementarity between Workplace Reorganization and New Technology [PDF]
We link survey and balance sheet data to investigate the extent of complementarity between the introduction of new technology and changes in workplace practices.
Alessandro Gaj +2 more
core
Objective Mycophenolate Mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon due to the lower fibrotic burden and the predominance of the vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis +77 more
wiley +1 more source
Il rilievo con drone nei centri storici
The survey with an UAV in the city centre for a research project of the University of L'Aquila has been started the use of UAV technology in some areas damaged by the earthquake of 2009.
Zaira Baglione
doaj

