Results 211 to 220 of about 11,464 (289)

Development and Optimization of a Nanophytosomes‐Based Thermogel as a Topical Anti‐Psoriatic for Increased Solubility and Bioavailability

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
Schematic illustration of the development, optimization, and therapeutic evaluation of the Leucas aspera phytosome‐based thermogel for topical antipsoriatic therapy, highlighting its enhanced solubility, skin deposition, and in vivo efficacy in an imiquimod‐induced psoriasis model. Created with BioRender.com.
Ananda Kumar Chettupalli   +2 more
wiley   +1 more source

Preclinical Efficacy and Safety Study of a Novel Dermal Fibroblast Modulating Drug, SLI‐F06, in Cutaneous Wound Healing

open access: yesMedComm, Volume 7, Issue 6, June 2026.
A novel, chemically synthesized fibromodulin (FMOD)‐derived peptide, SLI‐F06, has been developed to significantly improve scar appearance, tensile strength, and histological outcomes among multiple preclinical animal models. Demonstrating no genotoxicity or systemic/local toxicity, SLI‐F06 has received United States Food and Drug Administration ...
Zhong Zheng   +9 more
wiley   +1 more source

Evaluation of Photophysical Properties and Biological Applications of Diarylmethanes

open access: yesChemistryOpen, Volume 15, Issue 6, June 2026.
The wide applications of diarylmethanes were investigated through various experimental and computational approaches. The solvent environment influences the electronic properties of diarylmethanes and hence their drug‐like properties. Interactions with PARP1 revealed stable binding supporting anticancer potential.
H. Ranjini Jenifer   +2 more
wiley   +1 more source

Magnetic Nickel‐Containing Heterogeneous Catalysts for the Heck Reaction: Catalyst Design, Performance, and Sustainability

open access: yesChemistryOpen, Volume 15, Issue 6, June 2026.
This schematic outlines a general Heck coupling using magnetic nickel‐based catalysts. The reactants are mixed and heated to promote carbon–carbon bond formation and produce a substituted alkene product. After completion, an external magnet enables rapid separation of the nickel catalyst from the reaction mixture.
Forouzan Karimi   +3 more
wiley   +1 more source

The Dithiirane–Thiosulfine Equilibrium Revisited—A Computational Study of Structure, Thermodynamics and Kinetics

open access: yesJournal of Physical Organic Chemistry, Volume 39, Issue 6, June 2026.
The dithiirane–thiosulfine equilibrium has been revisited by means of modern computational chemistry tools to shed light on whether stable thiosulfines might be isolated. ABSTRACT Thiosulfines as reactive S‐centered 1,3‐dipoles undergoing (3 + 2)‐cycloadditions are still of interest in the chemistry of sulfur‐rich heterocycles.
Dirk Buddensiek, Thomas Behrens
wiley   +1 more source

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