Results 61 to 70 of about 1,175 (148)

Immunosenescence Profile Is Associated With Increased Susceptibility to Severe COVID‐19

Aging Cell, Volume 24, Issue 7, July 2025.
(A) A previous immunosenescence profile in individuals infected with SARS‐CoV2 creates a permissive environment for progression to severe COVID‐19: higher inflammaging, accumulation of exhausted/senescent T cells, an oligoclonal B‐cell repertoire, and accelerated epigenetic age.
Lucas Haniel A. Ventura, Lícia Torres, Giovanna Caliman Camatta, Jofer Zamame, Monique Macedo Coelho, Cecília Horta Ramalho‐Pinto, João Gervazio, Felipe Caixeta, Leandro Nascimento, Mariana Almeida Oliveira, Vinícius Dantas Martins, Marcos Felipe Oliveira, Murilo Soares Costa, Hugo Itaru Sato, Henrique Cerqueira Guimarães, Rafael Calvão Barbuto, Ana Paula Rocha Veiga, Najara Ataíde, Gabriela Prandi Caetano, Sarah Rangon, Mauro Lúcio O. Júnior, Fernanda Calvo Fortes, Luciana Zuccherato, Elaine Speziali, Olindo Assis Martins‐Filho, Verônica Coelho, Roberto Avritchir, Rafael Souza, Marina Ayupe, Caio Loureiro, Maria Eduarda Passos, Ana Clara Mota Neves, Pauline Leite, Santuza Maria Ribeiro Teixeira, Unaí Tupinambás, Liza Figueiredo Felicori, Gabriela Silveira‐Nunes, Tatiani Uceli Maioli, Denise Morais Fonseca, Andrea Teixeira‐Carvalho, Ana Maria Caetano Faria   +40 more
wiley   +1 more source

Ventilación con liberación de presión en la vía aérea y posición prono en el síndrome de distrés respiratorio agudo grave por SARS-CoV-2: reporte de caso

Revista Médica Clínica Las Condes
Resumen: COVID-19 tuvo un amplio espectro de manifestaciones clínicas, desde formas asintomáticas hasta graves. Un porcentaje significativo de sujetos infectados desarrolla el síndrome de distrés respiratorio agudo (SDRA). Objetivo: uso de posición prono
Rita Pino-Pino, Emilia Guajardo-Moyano, Felipe Castillo-Merino, Sebastián Ugarte-Ubiergo   +3 more
doaj   +1 more source

A pharmacokinetic framework describing antibiotic adsorption to cardiopulmonary bypass devices

CPT: Pharmacometrics &Systems Pharmacology, Volume 13, Issue 8, Page 1409-1421, August 2024.
Abstract Cardiopulmonary bypass (CPB) can alter pharmacokinetic (PK) parameters and the drug may adsorb to the CPB device, altering exposure. Cefazolin is a beta‐lactam antibiotic used for antimicrobial prophylaxis during cardiac surgery supported by CPB. Adsorption of cefazolin could result in therapeutic failure. An ex vivo study was undertaken using
Conor J. O'Hanlon, Nick Holford, Brian J. Anderson, Mark Greaves, Lee Blackburn, Malcolm D. Tingle, Jacqueline A. Hannam   +6 more
wiley   +1 more source

Esophageal pressure balloon and transpulmonary pressure monitoring in airway pressure release ventilation: a different approach

Canadian Journal of Respiratory Therapy, 2018
This is a case of Acute Respiratory Distress Syndrome managed using esophageal balloon catheter to adjust inspiratory pressure and positive end expiratory pressure according to the inspiratory and expiratory transpulmonary pressures. There are no studies
Daoud Ehab G., Yamasaki Kimiyo H., Nakamoto Keith, Wheatley Denise   +3 more
doaj   +1 more source

The Contemporary Presidency: Which presidents win more or less than expected in Congress? A Biden update

Presidential Studies Quarterly, Volume 54, Issue 2, Page 271-283, June 2024.
Abstract This article updates estimates of which presidents won more or fewer votes than should be expected through President Biden's first two years in office. Multiple regression models estimating the effects of contextual variables (party, public approval, and party polarization plus interactions) establish a common baseline.
Jon R. Bond
wiley   +1 more source

Airway pressure release ventilation mode in lung injury [PDF]

Airway pressure release ventilation (APRV) is a promising, unconventional mode of ventilation for the treatment of various respiratory diseases, including acute respiratory distress syndrome (ARDS).
Al-Ahmad, Abdullmohsen Mohammed
core   +3 more sources

Management of primary blast lung injury: a comparison of airway pressure release versus low tidal volume ventilation

Intensive Care Medicine Experimental, 2020
Background Primary blast lung injury (PBLI) presents as a syndrome of respiratory distress and haemoptysis resulting from explosive shock wave exposure and is a frequent cause of mortality and morbidity in both military conflicts and terrorist attacks ...
Timothy E. Scott, Anup Das, Mainul Haque, Declan G. Bates, Jonathan G. Hardman   +4 more
doaj   +1 more source

Time controlled adaptive ventilation™ as conservative treatment of destroyed lung: an alternative to lung transplantation

BMC Pulmonary Medicine, 2021
Background Acute respiratory distress syndrome (ARDS) often requires controlled ventilation, yielding high mechanical power and possibly further injury.
Malou Janssen, J. Han. J. Meeder, Leonard Seghers, Corstiaan A. den Uil   +3 more
doaj   +1 more source

Airway Pressure Release Ventilation setting disagreements. A survey of clinicians

Journal of Mechanical Ventilation, 2020
Background: Airway pressure release ventilation has been available to clinicians for the last four decades. Unfortunately, its clinical value continues to be debatable. One of the many reasons responsible is the lack of consistency between its settings
Ehab G. Daoud, Sandeep Randhawa , Ryota Sato   +2 more
doaj   +1 more source

Compared to conventional ventilation, airway pressure release ventilation may increase ventilator days in trauma patients

, 2012
BACKGROUND: Airway pressure release ventilation (APRV) is used both as a rescue therapy for patients with acute lung injury and as a primary mode of ventilation.
Davis, Kimberly A, Ditillo, Michael F, Schuster, Kevin M, Johnson, Dirk C, Kaplan, Lewis J, Maerz, Linda L, Lui, Felix Y, Maung, Adrian A, Piper, Greta L   +8 more
core   +1 more source