Results 161 to 170 of about 455,903 (227)
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 486-494, March 2025.Abstract The pharmaceutical industry has increasingly adopted model‐informed drug discovery and development (MID3) to enhance productivity in drug discovery and development. Quantitative systems pharmacology (QSP), which integrates drug action mechanisms and disease complexities to predict clinical endpoints and biomarkers is central to MID3.
Hiroaki Iwata, Ryuta Saito
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Rare Metals, EarlyView.ABSTRACT Rare earth elements (REEs) play an irreplaceable role in modern technology and industry. However, due to the highly similar physicochemical properties among REEs, their separation remains a significant challenge. Additionally, REEs often exist in low‐concentration solutions, making efficient REE recovery an urgent task.
Miao‐Miao Huang +6 more
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Rare Metals, EarlyView.ABSTRACT This study elucidates the oxidation mechanisms governing Y/Hf‐doped AlCoCrFeNiTi high‐entropy alloys (HEAs) and reveals the pivotal role of fabrication processes in dictating high‐temperature oxidation behavior. We demonstrate that casting and spark plasma sintering (SPS) promote Y/Hf segregation, resulting in heterogeneous oxide formation and
Huaqing Yi +5 more
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Strategic Management Journal, EarlyView.Abstract Research Summary We investigate how firm performance feedback and economic conditions (upturns and downturns) impact changes in the breadth of partner types within a firm's R&D alliance portfolio (R&D AP breadth). We theorize that economic conditions moderate firms' motivation to change R&D AP breadth in response to social and historical ...
Shiko M. Ben‐Menahem +2 more
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Substrate‐Tight Graphene Transmembrane‐nanofluidic Devices
Small, EarlyView.This study demonstrates that the covalent coupling of a pyrene layer to a silicon nitride substrate using silane and peptide chemistry increases the adhesion of graphene to the substrate and prevents the delamination of graphene. 76.2% of the devices with free‐standing graphene are successful devices for ion transport measurement in 0.1 M HCl ...
Xiaofang Kang +7 more
wiley +1 more source
2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions
Small, EarlyView.Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom +6 more
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An Oxygen‐Scavenger Sulfide Coating Enabling Long‐Term Stable Nickel‐Rich Cathodes
Small, EarlyView.ZrS2 as a novel coating can scavenge oxygen released from NMC lattices while converting to Zr(SO4)2. In return, such a sulfide‐sulfate conversion results in many benefits leading to high‐performance NMC cathodes. Abstract Oxygen release is a major issue associated with layer‐structured metal oxide cathodes in lithium batteries, which can further cause ...
Kevin Velasquez Carballo +7 more
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Small Methods, EarlyView.Time‐resolved synchrotron X‐ray scattering coupled with mechanochemical synthesis reveals the structural evolution of oxyhalide superionic conductors. Oxygen incorporation governs reaction kinetics, amorphization, and microstructural transformations, while enabling efficient Li‐ion diffusion. This study highlights critical correlations between reaction
Denys Butenko +15 more
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Conductive Hydrogel‐Enabled Electrode for Scalp Electroencephalography Monitoring
Small Methods, EarlyView.Conductive hydrogels are emerging as effective EEG electrode‐scalp interfaces to overcome hair barriers. This review presents the demanding parameters for hair‐compatible hydrogel electrodes and summarizes their applications in healthcare and brain‐computer interfaces.
Zichong Ji +14 more
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