Results 81 to 90 of about 87,926 (266)

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

Advanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim, Huajie Wang, Gao Qianqian, Abdul Waris, Jufang He   +4 more
wiley   +1 more source

Pelagic seabirds in coastal waters of the Western Ligurian Sea: occurrence and seasonality

Avocetta
Seabirds are an heterogeneous group of birds that, due to their behaviour and at-sea distribution, remain difficult to study when compared to other species.
Andrea Carolina Pedrazzini, Davide Ascheri, Enrico Carta, Léna Collet, Francesca Salvioli, Elena Fontanesi   +5 more
doaj   +1 more source

Versatile DNA‐Functionalized Biohybrid Hydrogel Platforms for Electrothermally Activated On‐Demand Payload Release

Advanced Science, EarlyView.
A DNA‐functionalized biohybrid hydrogel is developed by integrating Cu‐mediated nucleic acid microflowers into a thermoresponsive matrix, enabling electrothermally triggered, on‐demand payload release. The platform offers spatiotemporally controllable therapeutic delivery with promising applications in precision oncology, neural regulation, and chronic
Mengqiu Sun, Zhenshuai Tang, Jia Zhang, Rui Song, Wei Luo, Juan Huang, Jincheng Zeng, Zhen He, Hao Zhang   +8 more
wiley   +1 more source

Analysis on the mode of depletion of water reserves contained in the Locoli aquifer (Monte Albo - northeastern Sardinia)

Acque Sotterranee
This paper presents analytical insights based on hydrogeological monitoring data collected in a specific portion of Monte Albo, the Locoli aquifer, located in the Mesozoic limestones of north-eastern Sardinia: these analyses were carried out by ...
Francesco Murgia, Andrea Marassich, Sven Bertelmann, Marcello Iacca, Dorota Czerny, Olga Martinelli   +5 more
doaj   +1 more source

Fluorescence Tuning of Carbon Dots from Red to Blue via UV‐Induced Photochemical Etching

Advanced Science, EarlyView.
A UV‐driven photochemical process enables continuous color evolution of carbon dots from red to blue using a single irradiation parameter. Progressive photoetching restructures graphitic domains and surface states, allowing full visible‐spectrum emission control.
Nanzhi Zheng, Yuchen Yang, Jingwei Xu, Jincheng Gan, Yinuo An, Xinyu Li, Guohua Chen   +6 more
wiley   +1 more source

Epitope‐Resolved Digital SERS Profiling of Structurally Dynamic Antigens via a Multi‐Epitope Bispecific Antibody Framework

Advanced Science, EarlyView.
A multi‐epitope digital surface‐enhanced Raman spectroscopy framework enables epitope‐resolved immunoprofiling by integrating bispecific antibody fragments with spectrally encoded nanotags. This approach decouples binding events into independent digital channels, allowing structure‐aware antigen analysis.
Jing Wang, Quan Zhou, Kym Lowry, Christopher B. Howard, Matt Trau   +4 more
wiley   +1 more source

Electrical‐Stimulation Hydrogel Electronic Skin for Sustainable Hybrid Biomechanical–Electromagnetic Energy Harvesting and Accelerating Wound Healing

Advanced Science, EarlyView.
A hybrid biomechanical–electromagnetic energy‐harvesting e‐skin is developed using a gelatin‐based outer matrix with a zwitterionic conductive inner layer. The e‐skin autonomously generates stable electrical stimulation from daily body motion and ambient electronics, enabling significantly enhanced wound healing bothin vitro and in vivo.
Syun‐Hong Chou, Ming‐Han Lu, Wei‐Chen Peng, Wei‐Chun Yang, Pei‐Yi Liu, Yu‐Hsuan Yang, Yi‐Lin Huang, Cheng‐Hung Tsai, Ting‐Yu Yang, Xuan Zhang, Zhi‐Xian Yan, Ying‐Chih Lai, San‐Yuan Chen   +12 more
wiley   +1 more source

Bridged h‐BN Nanosheets Coatings: Simultaneous Shielding Atomic‐Oxygen Irradiation and Achieving Superior Friction Performance

Advanced Science, EarlyView.
ABSTRACT To confront extreme space environments, a combination of inorganic and organic coatings can provide a pathway for offering highly durable radiation resistance and anti‐friction simultaneously. Herein, a strong interfacial 3D hydrogen‐bonding network is designed to create robust hexagonal boron nitride (h‐BN) based polymer coatings with ...
Zhuoyi Li, Changning Bai, Xingkai Zhang, Yusheng Liang, Wei Wu, Dingrui Zhou, Tao Du, Chunjin Wang   +7 more
wiley   +1 more source

Plasmapheresis for lowering the risks of placenta-associated complications in antiphospholipid syndrome

Акушерство, гинекология и репродукция
Aim: to study plasmapheresis (PP) effect on antiphospholipid syndrome (APS) treatment during preconception preparation and pregnancy.Materials and Methods. A single-center, prospective, randomized, uncontrolled study was conducted.
N. F. Kuneshko, V. V. Kim, E. M. Lyadnova, A. R. Metkina, M. N. Velieva, A. V. Lazarchuk, V. O. Bitsadze, M. V. Tretyakova, D. V. Blinov   +8 more
doaj   +1 more source

Validity of biopsy-based drug effects in a diet-induced obese mouse model of biopsy-confirmed NASH

BMC Gastroenterology, 2019
Background Compounds in clinical development for nonalcoholic steatohepatitis (NASH) improve liver histopathology in diet-induced obese mouse models of biopsy-confirmed NASH. Since the biopsy section used for histopathological evaluation represents only
Maria Nicoline Baandrup Kristiansen, Sanne Skovgård Veidal, Christina Christoffersen, Michael Feigh, Niels Vrang, Jonathan David Roth, Mary Erickson, Luciano Adorini, Jacob Jelsing   +8 more
doaj   +1 more source