Results 171 to 180 of about 833 (196)

Analytical Quality by Design (AQbD) as a multiaddressable platform for co-encapsulating drug assays

Analytical Methods, 2018
AQbD provided a comprehensive framework for developing a reliable, effective, flexible band robust method for the routine analysis of the compounds in quality control laboratories.
João Basso, Maria Mendes, Tânia F. G. G. Cova, João J. Sousa, Alberto A. C. C. Pais, Carla Vitorino   +5 more
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Development of an AQbD driven HPLC method for the simultaneous estimation of caffeine and misoprostol in nanoparticle formulations

Analytical Methods
This graphical abstract depicts the HPLC-based simultaneous estimation of caffeine and misoprostol using, AQbD, followed by quantitative analysis of both drugs in chitosan based nanoparticles.
Nitasha Chauhan, Shiv Kumar, Shailendra Singh Rana, Shruti Chopra, Amit Bhatia   +4 more
openaire   +2 more sources

A Mini Overview of Analytical Quality by Design (AQbD)

A methodical, science- and risk-based approach to pharmaceutical development, Quality by  Design (QbD) emphasizes incorporating quality into goods rather than depending just on end product testing. Through standards like ICH Q8 (Pharmaceutical Development), Q9 (Quality Risk  Management), and Q10 (Pharmaceutical Quality System), regulatory bodies ...
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Analytical Quality by Design (AQbD): A Comprehensive Review with Emphasis on Risk Assessment Approaches

International Journal of Research in Pharmacy and Allied Science
Analytical Quality by Design (AQbD) is an innovative framework that enhances the robustness, reliability, and regulatory compliance of analytical methods through a systematic, science- and risk-based approach. This review article provides a comprehensive overview of the AQbD paradigm, with a particular emphasis on the integration and application of ...
Palak Jethava, Dr. Nilesh Patel
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Comprehensive review on Alfuzosin quantification: Analytical techniques and the evolution of AQbD in method development

International Journal of Research in Pharmacy and Allied Science
Alfuzosin is an alpha-adrenergic antagonist that is used in the treatment of benign prostatic hyperplasia. With a focus on spectroscopic and chromatographic techniques, this review critically examines the many analytical procedures developed for alfuzosin evaluation.
Patlolla Pravalika, Jaggayagari Sarika, Panuganti Pranavi, Kondam Rithikesh, Tadikonda Rama Rao   +4 more
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Development of UHPLC method for the analysis of pimavanserin and its impurities using AQbD principles

2020
Traditional approach to method development based on varying one-factor-at-a-time (OFAT), especially from the industry point of view, is time-consuming and therefore extremely expensive process. In recent years, development of analytical methods is based on the principles of analytical quality by design (AQbD) as a part of a full risk assessment ...
Radić, Irena, Lasić, Zlata, Runje, Mislav, Babić, Sandra   +3 more
openaire   +2 more sources

Analytical quality-by-design (AQbD) guided development of a robust HPLC method for the quantification of plumbagin from Plumbago species

Journal of Liquid Chromatography and Related Technologies, 2021
Amit Kumar, Pavitra Solanki, Mahaveer Dhobi   +2 more
exaly  

Development and optimization of a LC-MS/MS compatible method for quantification of losartan, hydrochlorothiazide and their impurities using AQbD approach and measurement uncertainty evaluation

Talanta, 2023
Felipe R Lourenço
exaly  

Fractional factorial and central composite design for implementation of risk and DoE-based enhanced AQbD approach to eco-friendly HPTLC method for estimation of dalfampridine in pharmaceutical dosage forms and human plasma

Journal of the Iranian Chemical Society, 2021
Pintu B Prajapati, Shailesh A Shah
exaly  

ANALYTICAL QUALITY BY DESIGN (AQBD) APPROACH FOR LIFECYCLE MANAGEMENT OF PHARMACEUTICAL ANALYTICAL METHODS

The pharmaceutical industry has increasingly adopted science- and risk-based approaches to ensure the quality, safety, and efficacy of pharmaceutical products. One of the most widely implemented strategies is Quality by Design (QbD), which emphasises systematic product and process understanding during drug development.
openaire   +1 more source